Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving hundreds of leading biopharmaceutical companies globally:

US Army
Merck
UBS
Chubb
Fish and Richardson
McKesson
Boehringer Ingelheim
Moodys
Accenture

Generated: May 23, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,288,726

« Back to Dashboard

Summary for Patent: 5,288,726
Title: Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation
Abstract:Compounds of formula (I): ##STR1## wherein: R.sup.1 is hydrogen, alkyl, halogen, haloalkyl, hydroxy, alkoxy, haloalkoxy, alkylthio, haloalkylthio, amino, alkanoyl, haloalkanoyl, carboxy, alkoxycarbonyl, carbamoyl, cyano, nitro, alkanesulfonyl, haloalkanesulfonyl or sulfamoyl; R.sup.2 is optionally substituted alkanoyl, optionally substituted alkenoyl, optionally substituted cycloalkylcarbonyl, substituted benzoyl, or 5,6-dihydro-1,4,2-dioxazin-3-yl; R.sup.3 is hydrogen, hydroxy, optionally substituted alkoxy, aralkyloxy, alkanoyloxy, alkenoyloxy, cycloalkylcarbonyloxy, arylcarbonyloxy, alkoxycarbonyloxy, aralkyloxycarbonylxy, phthalidyloxy, (5-methyl-2-oxo-1,3-dioxolen-4-yl)methoxy, (5-phenyl-2-oxo-1,3-dioxolen-4-yl)methoxy, optionally substituted amino or nitro; Y is --NH-- or oxygen or sulfur; n is 1 to 5; and tautomers and salts of said compounds of formula (I), have the ability to inhibit blood platelet aggregation, and can thus be used for treatment and prophylaxis of thrombosis and embolisms.
Inventor(s): Koike; Hiroyuki (Tokyo, JP), Asai; Fumitoshi (Tokyo, JP), Sugidachi; Atsuhiro (Tokyo, JP), Kimura; Tomio (Ube, JP), Inoue; Teruhiko (Ube, JP), Nishino; Shigeyoshi (Ube, JP), Tsuzaki; Yasunori (Ube, JP)
Assignee: Ube Industries Limited (Ube, JP) Sankyo Company, Limited (Tokyo, JP)
Application Number:07/941,676
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 5,288,726
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Drugs Protected by US Patent 5,288,726

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

Foreign Priority and PCT Information for Patent: 5,288,726

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan3-227875Sep 09, 1991
Japan4-138529May 29, 1992

International Family Members for US Patent 5,288,726

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
China 1217186 ➤ Try a Free Trial
China 1107502 ➤ Try a Free Trial
Czech Republic 9202784 ➤ Try a Free Trial
Czech Republic 287181 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

UBS
Moodys
Boehringer Ingelheim
Cipla
McKinsey
Johnson and Johnson
Deloitte
Cantor Fitzgerald
Baxter

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.