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Generated: December 15, 2017

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Details for Patent: 5,284,662

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Summary for Patent: 5,284,662

Title: Oral osmotic system for slightly soluble active agents
Abstract:An oral sustained release composition for slightly soluble pharmaceutically active agents comprising a core, a wall around said core, and a bore through said wall connecting said core and the environment outside of said wall; wherein said core comprises a slightly soluble active agent, optionally a crystal habit modifier, at least two osmotic driving agents, at least two different (or two different grades of) hydroxyalkyl celluloses, and optionally lubricants, wetting agents, and carriers; said wall being substantially impermeable to said core components and permeable to water and gastro-intestinal fluids. The composition is most especially adapted for administering carbamazepine.
Inventor(s): Koparkar; Arun D. (Westfield, NJ), Shah; Shailesh B. (Union, NJ)
Assignee: Ciba-Geigy Corp. (Ardsley, NY)
Application Number:07/809,026
Patent Claim Types:
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Delivery; Composition; Dosage form;

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Serving leading biopharmaceutical companies globally:

Cantor Fitzgerald
Johnson and Johnson
US Department of Justice
Boehringer Ingelheim

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