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|Title:||Pravastatin pharmaceuatical compositions having good stability|
|Abstract:||A pharmaceutical composition is provided which has excellent stability, when dispersed in water has a pH of at least about 9, and includes a medicament which is sensitive to a low pH environment such as pravastatin, one or more fillers such as lactose and/or microcrystalline cellulose, one or more binders, such as microcrystalline cellulose (dry binder) or polyvinylpyrrolidone (wet binder), one or more disintegrating agents such as croscarmellose sodium, one or more lubricants such as magnesium stearate and one or more basifying agents such as magnesium oxide.|
|Inventor(s):||Joshi; Yatindra M. (Piscataway, NJ), Chiesa; Pierina (South Orange, NJ), Jain; Nemichand B. (Monmouth Junction, NJ)|
|Assignee:||E. R. Squibb & Sons, Inc. (Princeton, NJ)|
Patent Claim Types:|
see list of patent claims
|Composition; Dosage form; Use;|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|Australia||624117||<disabled in preview>|
|Canada||1323836||<disabled in preview>|
|China||1036508||<disabled in preview>|
| This preview shows a limited data set|
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.
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