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|Title:||Sulphated glycosaminoglycuronan with antithrombotic activity|
|Abstract:||The present invention relates to sulphated glycosamino glycuronan with antithrombotic activity consisting essentially of salts of dermatan sulphate, chondroitin sulphate and heparan sulphate, characterized by a) an average molecular weight between 4000 and 8000 daltons; b) a nitrogen content between 2.4 and 3.0%; c) a sulphur content between 7.5 and 9.5%; d) a sodium content between 9 and 11%; e) a dermatan sulphate content between 5 and 25%; f) a chondroitin sulphate content less than 9%; g) an anti-Xa activity between 11 and 20 .mu./mg; and h) an antithrombin III dependent antithrombin activity of less than 1 .mu./mg.|
|Inventor(s):||Van Dedem; Gijsbert W. K. (Oss, NL), Van Hou Denhoven; Francois E. A. (Heesch, NL), Meuleman; Dirk G. (Oss, NL), Moelker; Huibert C. T. (Megen, NL), Sanders; Adrianus L. M. (Uden, NL)|
|Assignee:||Akzo N.V. (Arnhem, NL)|
Patent Claim Types:|
see list of patent claims
|Compound; Formulation; Device; Composition;|
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|89202494.4||Oct 04, 1989|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
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