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Serving hundreds of leading biopharmaceutical companies globally:

McKesson
Express Scripts
Moodys
Covington
US Army
Federal Trade Commission
Merck
Cantor Fitzgerald
US Department of Justice

Generated: May 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,130,120

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Summary for Patent: 5,130,120
Title: Paramagnetic DTPA and EDTA alkoxyalkylamide complexes as MRI agents
Abstract:Novel magnetic resonance imaging agents and methods which utilize complexes of paramagnetic ions with alkoxyalkylamide derivatives of diethylenetriaminepentaacetic acid ("DTPA") or ethylenediaminetetraacetic acid ("EDTA"). These novel imaging agents are characterized by excellent NMR image-contrasting properties and by high solubilities in physiological solutions. The complexes are represented by the following formula: ##STR1## wherein A is --CH.sub.2 CH.sub.2 -- or ##STR2## and M.sup.+z is a paramagnetic ion of an element with an atomic number of 21-29, 42-44 or 58-70, and a valence, Z, of 2 or 3; the R groups may be the same or different and are selected from the group consisting of -O.sup..crclbar. and lower alkoxyalkylamino groups having from 2 to about 6 carbon atoms, wherein the number of R groups -O.sup..crclbar. equals Z and the remaining R groups are lower alkoxyalkylamino, equal to 4-Z when A is --CH.sub.2 CH.sub.2 --, or 5-Z when A ##STR3##
Inventor(s): Weber; Robert W. (Downingtown, PA)
Assignee: Mallinckrodt Medical, Inc. (St. Louis, MO)
Application Number:07/221,425
Patent Claim Types:
see list of patent claims
Compound; Composition; Dosage form; Use;

Drugs Protected by US Patent 5,130,120

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Serving hundreds of leading biopharmaceutical companies globally:

McKesson
Farmers Insurance
Accenture
QuintilesIMS
Merck
Fuji
Chinese Patent Office
Cipla
Baxter

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