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|Abstract:||The present invention relates to a new two-component pharmaceutical formulation of melphalan in which the two components comprise (a) freeze-dried mephalan hydrochloride and (b) a solvent-diluent comprising a citrate, propylene glycol and ethanol. Substantially pure melphalan, substantially pure melphalan hydrochloride and methods for preparing them are also described.|
|Inventor(s):||Poole; Stephen W. (Dartford, GB2), Stanley; Timothy P. (Dartford, GB2), Divall; Geoffrey (Dartford, GB2), Packham; Terence W. (Dartford, GB2), Knight; Joseph (Dartford, GB2)|
Patent Claim Types:|
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|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|United Kingdom||8727157||Nov 19, 1987|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
| This preview shows a limited data set|
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Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.
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