|Title:||8-alkoxyquinolonecarboxylic acid and salts thereof|
|Abstract:||Quinolonecarboxylic acid derivatives of the following formula: ##STR1## wherein R indicates a hydrogen atom or lower alkyl group, R.sup.1 indicates a lower alkyl group, R.sup.2 indicates a hydrogen atom, amino group or nitro group, X indicates a halogen atom, and Z indicates a halogen atom, piperazino group, N-methylpiperazino group, 3-methylpiperazino group, 3-hydroxypyrrolidino group, or pyrrolidino group of the following formula, ##STR2## (here, n is 0 or 1, R.sup.3 indicates a hydrogen atom or lower alkyl group, R.sup.4 indicates a hydrogen atom, lower alkyl group and R.sup.5 indicates a hydrogen atom, lower alkyl group, acyl group or alkoxycarbonyl group), the hydrates and pharmaceutically acceptable salts thereof are useful as antibacterial agents.|
|Inventor(s):||Masuzawa; Kuniyoshi (Koga, JP), Suzue; Seigo (Kuki, JP), Hirai; Keiji (Kuki, JP), Ishizaki; Takayoshi (Saitama, JP)|
|Assignee:||Kyorin Pharmaceutical Co., Ltd. (Tokyo, JP)|
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