Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving leading biopharmaceutical companies globally:

Federal Trade Commission
Daiichi Sankyo
US Department of Justice

Generated: December 10, 2017

DrugPatentWatch Database Preview

Details for Patent: 4,927,814

« Back to Dashboard

Summary for Patent: 4,927,814

Title: Diphosphonate derivatives, pharmaceutical compositions and methods of use
Abstract:The present invention provides disphosphonates of the general formula: ##STR1## wherein R.sub.1 is a straight-chain or branched, saturated or unsaturated aliphatic hydrocarbon radical of 1-9 carbon atoms which is optionally substituted by phenyl or cyclohexyl, R.sub.2 is cyclohexyl or cyclohexylmethyl, benzyl or a straight-chained or branched, saturated or unsaturated aliphatic hydrocarbon of 4 to 18 carbon atoms which is optionally substituted by phenyl or oxygen wherein the oxygen can be esterified or etherified, R.sub.3 is hydrogen or a straight-chain or branched alkyl of 1-4 carbon atoms, X is a straight-chain or branched alkylene chain of 1-6 carbon atoms and Y is hydrogen, hydroxyl or an amino group optionally substituted by alkyl radicals of 1-6 carbon atoms; as well as the pharmacologically acceptable salts thereof. The present invention also provides processes for the preparation of these diphosphonic acid derivatives and pharmaceutical compositions containing them for the prophyllaxis treatment of diseases or disturbances of calcium metabolism such as osteoporsis, Pagets disease, Bechterew's disease, bone metastases, urolithiasis, heterotropic ossifications, rheumatoid arthritis, osteoarthritis and degenerative arthrosis.
Inventor(s): Gall; Rudi (Hirschberg, DE), Bosies; Elmar (Weinheim, DE)
Assignee: Boehringer Mannheim GmbH (Mannheim, DE)
Application Number:07/071,471
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

No matches for this query

Foreign Priority and PCT Information for Patent: 4,927,814

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Germany3623397Jul 11, 1986

International Patent Family for Patent: 4,927,814

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria54000► Subscribe
Austria80633► Subscribe
Australia598279► Subscribe
Australia598569► Subscribe
Australia7529187► Subscribe
Australia7648787► Subscribe
Bulgaria60839► Subscribe
Canada1296739► Subscribe
Canada1305166► Subscribe
Czechoslovakia265242► Subscribe
This preview shows a limited data set
Subscribe for full access, or try a Trial

The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

Export unavailable in trial.
Subscribe for complete access.

For more information try a trial or see the database preview and plans and pricing

Serving leading biopharmaceutical companies globally:

Daiichi Sankyo
Johnson and Johnson
Cantor Fitzgerald

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

Copyright 2002-2017 thinkBiotech LLC
ISSN: 2162-2639

Secure SSL Encrypted
Privacy and Cookies
Terms & Conditions

Follow DrugPatentWatch: