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|Title:||Oral anti-diabetic pharmaceutical compositions and the preparation thereof|
|Abstract:||Galenic compositions containing an oral antidiabetic agent and having an improved release of active substance as well as processes for producing these compositions are provided. The pharmaceutical compositions are characterized in that the onset of the activity and the duration of activity are adapted to the particular needs of diabetics with regard to proper control of metabolism and the associated proper release of insulin. A basic or acidic excipient in a solvent is added to the anti-diabetically active substance in a quantity such that the active substance is made soluble, and then a solubilizing agent is added. The solution is applied to a water-insoluble carrier, the solvent is evaporated, and the residue is further processed to yield the various compositions.|
|Inventor(s):||Brickl; Rolf (Warthausen, DE), Schepky; Gottfried (Biberach, DE), Rupprecht; Eckhard (Aulendorf-Tannhausen, DE), Greischel; Andreas (Biberach, DE)|
|Assignee:||Dr. Karl Thomae GmbH (Biberach an der Riss, DE)|
Patent Claim Types:|
see list of patent claims
|Use; Composition; Formulation;|
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|Germany||3320583||Jun 08, 1983|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|United Kingdom||2142235||<disabled in preview>|
|United Kingdom||8414528||<disabled in preview>|
|Finland||85218||<disabled in preview>|
| This preview shows a limited data set|
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.
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