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Serving hundreds of leading biopharmaceutical companies globally:

Covington
Mallinckrodt
Daiichi Sankyo
Citi
Healthtrust
Colorcon
Boehringer Ingelheim
US Army
QuintilesIMS

Generated: May 27, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,863,970

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Summary for Patent: 4,863,970
Title: Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
Abstract:Penetration-enhancing pharmaceutical compositions for topical transepidermal and percutaneous application are disclosed which are non-irritating to the skin. These compositions are made up of a safe and effective amount of an active pharmaceutical permeant, including hydrophilic salt forms, contained in a novel penetration-enhancing vehicle comprising, (i) 1-95% w. of a cell-envelope disordering compound selected from the group consisting of oleic acid, oleyl alcohol, glycerol monoleate, glycerol dioleate, glycerol trioleate and mixtures thereof, (ii) 5-75% w., and preferably 5-49% w., of a lower alkanol selected from the group consisting of ethanol, propanol and isopropanol and mixtures thereof and (iii) 0-45% w., and preferably 1-45% w., of an inert diluent which, according to properties of the permeant used, may range from hydrophilic to hydrophobic. Water, polyethylene or polypropylene glycols and mineral oil are exemplary diluents.
Inventor(s): Patel; Dinesh C. (Murray, UT), Chang; Yunik (Lakewood, NJ)
Assignee: Theratech, Inc. (Salt Lake City, UT)
Application Number:07/218,702
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 4,863,970
Patent Claim Types:
see list of patent claims
Composition; Compound;

Drugs Protected by US Patent 4,863,970

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Family Members for US Patent 4,863,970

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 77559 ➤ Try a Free Trial
Germany 3779999 ➤ Try a Free Trial
European Patent Office 0267617 ➤ Try a Free Trial
Spain 2042527 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

US Department of Justice
Harvard Business School
Moodys
McKinsey
Merck
Accenture
McKesson
Citi
AstraZeneca

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