Pharmaceutical formulations of acid labile substances for oral use
Pharmaceutical preparation containing an acid labile compound together with an alkaline reacting compound or an alkaline salt of an acid labile compound optionally together with an alkaline compound as the core material, one or more subcoating layers comprising inert reacting compounds which are soluble or rapidly disintegrating in water, or polymeric, water soluble filmforming compounds, optionally containing pH-buffering alkaline compounds and an enteric coating as well as a process for the preparation thereof and the use in the treatment of gastrointestinal diseases.
Lovgren; Kurt I. (Molnlycke, SE), Pilbrant; Ake G. (Kungsbacka, SE), Yasumura; Mitsuru (Hyogo, JP), Morigaki; Satoshi (Hyogo, JP), Oda; Minoru (Ohita, JP), Ohishi; Naohiro (Fukuoka, JP)
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