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Generated: October 17, 2017
| Title: | Biologically active B-chain homodimers |
| Abstract: | Dimeric proteins having substantially the same biological activity as PDGF are disclosed. More specifically, the protein may have two substantially identical polypeptide chains, each of the chains being substantially homologous to the B-chain of PDGF. Alternatively, the protein may have two polypeptide chains that are substantially identical to the B-chain of PDGF. In addition, proteins comprising polypeptides that are variants or derivatives of the B-chain of PDGF are also disclosed. Therapeutic compositions containing these proteins and methods for enhancing the wound-healing process in warm-blooded animals are also disclosed. |
| Inventor(s): | Murray; Mark J. (Seattle, WA), Kelly; James D. (Seattle, WA) |
| Assignee: | ZymoGenetics, Inc. (Seattle, WA) |
| Application Number: | 06/942,161 |
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Patent Claim Types: see list of patent claims | Compound; Composition; Use; |
| Country | Document Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Austria | 131532 | ► Subscribe | |||||||||||||
| Austria | 188255 | ► Subscribe | |||||||||||||
| Austria | 84312 | ► Subscribe | |||||||||||||
| Australia | 4845485 | ► Subscribe | |||||||||||||
| Australia | 5488590 | ► Subscribe | |||||||||||||
| Australia | 638010 | ► Subscribe | |||||||||||||
| Australia | 641816 | ► Subscribe | |||||||||||||
| Australia | 7681687 | ► Subscribe | |||||||||||||
| Australia | 8695791 | ► Subscribe | |||||||||||||
| Canada | 1340212 | ► Subscribe | |||||||||||||
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
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Serving leading biopharmaceutical companies globally:
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