Last Updated: August 9, 2026

Details for Patent: 4,845,075

Name: Drug Patent Intelligence for US Patent 4845075
Creator: DrugPatentWatch
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Summary for Patent: 4,845,075

Title:	Biologically active B-chain homodimers
Abstract:	Dimeric proteins having substantially the same biological activity as PDGF are disclosed. More specifically, the protein may have two substantially identical polypeptide chains, each of the chains being substantially homologous to the B-chain of PDGF. Alternatively, the protein may have two polypeptide chains that are substantially identical to the B-chain of PDGF. In addition, proteins comprising polypeptides that are variants or derivatives of the B-chain of PDGF are also disclosed. Therapeutic compositions containing these proteins and methods for enhancing the wound-healing process in warm-blooded animals are also disclosed.
Inventor(s):	Mark J. Murray, James D. Kelly
Assignee:	Zymogenetics Inc
Application Number:	US06/942,161
Patent Claim Types: see list of patent claims	Use; Composition;

Drugs Protected by US Patent 4,845,075

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 4,845,075

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
European Patent Office	0177957	⤷ Start Trial	SPC/GB99/023	United Kingdom	⤷ Start Trial
European Patent Office	0177957	⤷ Start Trial	C990016	Netherlands	⤷ Start Trial
European Patent Office	0177957	⤷ Start Trial	99C0034	Belgium	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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