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Details for Patent: 4,845,075
Summary for Patent: 4,845,075
Title: | Biologically active B-chain homodimers |
Abstract: | Dimeric proteins having substantially the same biological activity as PDGF are disclosed. More specifically, the protein may have two substantially identical polypeptide chains, each of the chains being substantially homologous to the B-chain of PDGF. Alternatively, the protein may have two polypeptide chains that are substantially identical to the B-chain of PDGF. In addition, proteins comprising polypeptides that are variants or derivatives of the B-chain of PDGF are also disclosed. Therapeutic compositions containing these proteins and methods for enhancing the wound-healing process in warm-blooded animals are also disclosed. |
Inventor(s): | Murray; Mark J. (Seattle, WA), Kelly; James D. (Seattle, WA) |
Assignee: | ZymoGenetics, Inc. (Seattle, WA) |
Application Number: | 06/942,161 |
Patent Claim Types: see list of patent claims | Compound; Composition; Use; |
Drugs Protected by US Patent 4,845,075
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Patent Submitted |
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Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Patent Submitted |
International Family Members for US Patent 4,845,075
Country | Document Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
European Patent Office | 0177957 | ➤ Try a Free Trial | SPC/GB99/023 | United Kingdom | ➤ Try a Free Trial |
European Patent Office | 0177957 | ➤ Try a Free Trial | C990016 | Netherlands | ➤ Try a Free Trial |
European Patent Office | 0177957 | ➤ Try a Free Trial | 99C0034 | Belgium | ➤ Try a Free Trial |
Denmark | 176036 | ➤ Try a Free Trial | |||
Country | Document Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |