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Generated: May 24, 2018

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Details for Patent: 4,843,086

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Summary for Patent: 4,843,086
Title: Tetrahydro-benzthiazoles, the preparation thereof and their use as intermediate products or as pharmaceuticals
Abstract:This invention relates to new tetrahydrobenzthiazoles of general formula ##STR1## wherein R.sub.1 represents a hydrogen atom, an alkyl group, an alkenyl or alkynyl group, an alkanoyl group, a phenyl alkyl or phenyl alkanoyl group, while the above mentioned phenyl nuclei may each be substituted by 1 or 2 halogen atoms. R.sub.2 represents a hydrogen atom or an alkyl group, R.sub.3 represents a hydrogen atom, an alkyl group a cycloalkyl group, an alkenyl or alkynyl group, an alkanoyl group, a phenyl alkyl or phenyl alkanoyl group, while the phenyl nucleus may be substituted by fluorine, chlorine or bromine atoms, R.sub.4 represents a hydrogen atom, an alkyl group, an alkyl or alkenyl group, or R.sub.3 and R.sub.4 together with the nitrogen atom between them represent a pyrrolidino, piperidino, hexamethyleneimino or morpholino group, the enantiomers and the acid addition salts thereof. The compounds of general formula I above in which one of the groups R.sub.1 or R.sub.3 or both groups R.sub.1 and R.sub.3 represent an acyl group are valuable intermediate products for preparing the other compounds of general formula I which have valuable pharmacological properties. The new compounds may be prepared using methods known per se.
Inventor(s): Griss, deceased; Gerhart (late of Biberach, DE), Schneider; Claus (Ingelheim am Rhein, DE), Hurnaus; Rudolf (Biberach, DE), Kobinger; Walter (Vienna, AT), Pichler; Ludwig (Vienna, AT), Bauer; Rudolf (Wiesbaden, DE), Mierau; Joachim (Mainz, DE), Hinzen; Dieter (Zornheim, DE), Schingnitz; Gunter (Bad Kreuznach, DE)
Assignee: Boehringer Ingelheim KG (Ingelheim am Rhein, DE)
Application Number:07/124,197
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 4,843,086
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 4,843,086

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 4,843,086

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Germany34470751Dec 22, 1984
Germany3508947Mar 13, 1985

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Serving hundreds of leading biopharmaceutical companies globally:

Boehringer Ingelheim
Covington
Citi
Argus Health
Johnson and Johnson
Daiichi Sankyo
Julphar
Deloitte
Medtronic

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