Details for Patent: 4,816,470
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Summary for Patent: 4,816,470
Title: | Heterocyclic compounds |
Abstract: | Indole derivatives of the general formula (I) are disclosed: ##STR1## where R.sub.1 is H or an alkyl or alkenyl group, R.sub.2 is H, or an alkyl, alkenyl, aryl, aralkyl or cycloalkyl group; R.sub.3 is H or an alkyl group; R.sub.4 and R.sub.5 are independently H or an alkyl or propenyl group or together form an aralkylidene group; and Alk is an optionally substituted alkylene chain; and their physiologically acceptable salts and solutes. These compounds are potentially useful for the treatment of migraine and may be formulated as pharmaceutical compositions in conventional manner. Various methods for the production of the compounds are disclosed including a Fischer-indole cyclization process. |
Inventor(s): | Dowle; Michael D. (Hertford, GB2), Coates; Ian H. (Hertford, GB2) |
Assignee: | Glaxo Group Limited ( |
Application Number: | 06/789,831 |
Patent Claim Types: see list of patent claims | Compound; Use; Composition; |
Drugs Protected by US Patent 4,816,470
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 4,816,470
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
United Kingdom | 8216526 | Jun 07, 1982 |
International Family Members for US Patent 4,816,470
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Austria | 381933 | ⤷ Try a Trial | |||
Austria | A208483 | ⤷ Try a Trial | |||
Australia | 1544183 | ⤷ Try a Trial | |||
Australia | 566149 | ⤷ Try a Trial | |||
Belgium | 896986 | ⤷ Try a Trial | |||
Canada | 1199643 | ⤷ Try a Trial | |||
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