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Queensland Health

Generated: August 18, 2017

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Title: Heterocyclic compounds
Abstract:Indole derivatives of the general formula (I) are disclosed: ##STR1## where R.sub.1 is H or an alkyl or alkenyl group, R.sub.2 is H, or an alkyl, alkenyl, aryl, aralkyl or cycloalkyl group; R.sub.3 is H or an alkyl group; R.sub.4 and R.sub.5 are independently H or an alkyl or propenyl group or together form an aralkylidene group; and Alk is an optionally substituted alkylene chain; and their physiologically acceptable salts and solutes. These compounds are potentially useful for the treatment of migraine and may be formulated as pharmaceutical compositions in conventional manner. Various methods for the production of the compounds are disclosed including a Fischer-indole cyclization process.
Inventor(s): Dowle; Michael D. (Hertford, GB2), Coates; Ian H. (Hertford, GB2)
Assignee: Glaxo Group Limited (
Application Number:06/789,831
Patent Claim Types:
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Compound; Use; Composition;

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Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8216526Jun 07, 1982

International Patent Family for Patent: ► Subscribe

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria381933► Subscribe
AustriaA208483► Subscribe
Australia1544183► Subscribe
Australia566149► Subscribe
Belgium896986► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
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Serving 500+ biopharmaceutical companies globally:

Federal Trade Commission
Queensland Health
Harvard Business School
Daiichi Sankyo
Cantor Fitzgerald

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