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Serving hundreds of leading biopharmaceutical companies globally:

Cantor Fitzgerald
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US Army
Citi
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Chinese Patent Office

Generated: May 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,816,470

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Summary for Patent: 4,816,470
Title: Heterocyclic compounds
Abstract:Indole derivatives of the general formula (I) are disclosed: ##STR1## where R.sub.1 is H or an alkyl or alkenyl group, R.sub.2 is H, or an alkyl, alkenyl, aryl, aralkyl or cycloalkyl group; R.sub.3 is H or an alkyl group; R.sub.4 and R.sub.5 are independently H or an alkyl or propenyl group or together form an aralkylidene group; and Alk is an optionally substituted alkylene chain; and their physiologically acceptable salts and solutes. These compounds are potentially useful for the treatment of migraine and may be formulated as pharmaceutical compositions in conventional manner. Various methods for the production of the compounds are disclosed including a Fischer-indole cyclization process.
Inventor(s): Dowle; Michael D. (Hertford, GB2), Coates; Ian H. (Hertford, GB2)
Assignee: Glaxo Group Limited (
Application Number:06/789,831
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Drugs Protected by US Patent 4,816,470

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 4,816,470

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8216526Jun 07, 1982

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Serving hundreds of leading biopharmaceutical companies globally:

Federal Trade Commission
Queensland Health
Chinese Patent Office
Fuji
Argus Health
Covington
US Department of Justice
Cantor Fitzgerald
Dow

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