Deeper Knowledge, Faster

  • Analyze global market entry opportunities
  • Identify first generic entrants
  • Drug patents in 130+ countries

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving leading biopharmaceutical companies globally:

Daiichi Sankyo
Farmers Insurance
Boehringer Ingelheim
US Department of Justice

Generated: December 18, 2017

DrugPatentWatch Database Preview

Details for Patent: 4,777,163

« Back to Dashboard

Summary for Patent: 4,777,163

Title: Diphosphonate derivatives, pharmaceutical compositions and methods of use for calcium disturbances
Abstract:The present invention produces alkyldiphosphonic acid derivative of the general formula: ##STR1## wherein Het is a heteroaromatic five-membered ring containing to 3 heteroatoms which can be partly hydrogenated and optionally substituted one or more times by alkyl, alkoxy, phenyl, cyclohexyl, cyclohexylmethyl, halogen or amino, and two adjacent alkyl substituents can together also form a ring, Y is a hydrogen atom or a lower alkyl radical, X is a hydrogen atom, a hydroxyl group or an amino group optionally substituted by lower alkyl and R is a hydrogen atom or a lower alkyl radical, with the proviso that Het is not a pyrazole ring; as well as the pharmacologically acceptable salts thereof. The present invention also provides processes for the prepearation of these compounds and pharmaceutical compositions containing them useful for the treatment or prophylaxis of calcium metabolism disturbances or disease as for example osteoporosis, Bechterew's disease, bone metastases, urolithiasis, heterotropic ossifications, rheumatoid arthritis osteoarthritis or degenerative arthrosis.
Inventor(s): Bosies; Elmar (Weinheim, DE), Gall; Rudi (Hirschberg, DE)
Assignee: Boehringer Mannheim GmbH (Mannheim, DE)
Application Number:07/077,228
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

No matches for this query

Foreign Priority and PCT Information for Patent: 4,777,163

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Germany3626058Aug 01, 1986

International Patent Family for Patent: 4,777,163

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Denmark398187► Subscribe
Germany3778800► Subscribe
Germany3626058► Subscribe
German Democratic Republic264442► Subscribe
European Patent Office0258618► SubscribeSPC/GB01/042United Kingdom► Subscribe
European Patent Office0258618► Subscribe2001C/036Belgium► Subscribe
European Patent Office0258618► SubscribeC300059Netherlands► Subscribe
European Patent Office0258618► Subscribe26/2001Austria► Subscribe
Denmark168820► Subscribe
Germany10199050► Subscribe
This preview shows a limited data set
Subscribe for full access, or try a Trial

The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

Export unavailable in trial.
Subscribe for complete access.

For more information try a trial or see the plans and pricing

Serving leading biopharmaceutical companies globally:

Farmers Insurance

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

Copyright 2002-2017 thinkBiotech LLC
ISSN: 2162-2639

Secure SSL Encrypted
Privacy and Cookies
Terms & Conditions

Follow DrugPatentWatch: