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Serving hundreds of leading biopharmaceutical companies globally:

US Army
McKesson
Fish and Richardson
Medtronic
Fuji
Express Scripts
McKinsey
Deloitte
Argus Health

Generated: April 19, 2018

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Details for Patent: 4,753,789

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Summary for Patent: 4,753,789
Title: Method for treating nausea and vomiting
Abstract:The invention relates to the use of compounds of the general formula (I) ##STR1## wherein R.sup.1 represents a hydrogen atom or a C.sub.1-10 alkyl, C.sub.3-7 cycloalkyl, C.sub.3-7 cycoalkyl-(C.sub.1-4) alkyl, C.sub.3-6 alkenyl, C.sub.3-10 alkynyl, phenyl or phenyl-C.sub.1-3 alkyl group, and one of the groups represented by R.sup.2,R.sup.3 and R.sup.4 is a hydrogen atom or a C.sub.1-6 alkyl, C.sub.3-7 cycloalkyl, C.sub.2-6 alkenyl or phenyl - C.sub.1-3 alkyl group and each of the other two groups, which may be the same or different, represents a hydrogen atom or a C.sub.1-6 alkyl group; and physiologically acceptable salts and solvates thereof, for the relief of nausea and vomiting and/or the promotion of gastric emptying and for the manufacture of a medicament for this purpose. Promotion of gastric emptying may be for the relief of gastro-intestinal disorders associated with gastric stasis or may be of advantage of radiological examination procedures. The invention also relates to a product containing a therapeutic agent liable to induce nausea and vomiting, e.g. a cytostatic agent such as a cyclophosphamide, an alkylating agent or a platinum complex, and a compound of the general formula (I) as a combined preparation for simultaneous separate or sequential use in therapy.
Inventor(s): Tyers; Michael B. (Welwyn, GB2), Coates; Ian H. (Hertford, GB2), Humber; David C. (London, GB2), Ewan; George B. (Gerrards Cross, GB2), Bell; James A. (Royston, GB2)
Assignee: Glaxo Group Limited (GB2)
Application Number:06/877,805
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 4,753,789

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 4,753,789

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8516083Jun 25, 1985

International Patents Family Members for US Patent 4,753,789

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
France 2613934 ➤ Try a Free Trial
Hong Kong 82597 ➤ Try a Free Trial
United Kingdom 8516083 ➤ Try a Free Trial
United Kingdom 2200046 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Chubb
Express Scripts
Colorcon
Daiichi Sankyo
Boehringer Ingelheim
Harvard Business School
Johnson and Johnson
McKesson
QuintilesIMS

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