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Serving hundreds of leading biopharmaceutical companies globally:

UBS
AstraZeneca
US Army
Johnson and Johnson
Deloitte
Chubb
McKesson
McKinsey
Argus Health

Generated: May 26, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,704,282

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Summary for Patent: 4,704,282
Title: Transdermal therapeutic system having improved delivery characteristics
Abstract:A transdermal therapeutic system using a subsaturated matrix is provided having improved approved release characteristics. Reinforcing means preferably in the form of a fabric are embedded in the upper surface of the subsaturated matrix. At least a portion of the reinforcing means is selected such that the active agent to be delivered to the skin has a solubility, C.sub.r therein which is lower than the initial solubility C.sub.o of the agent in the matrix. In addition, the relationship between the diffusion coefficients of the agent in the matrix D.sub.m and the portion of reinforcing means D.sub.r and the solubilities is given by the relationship: D.sub.r .multidot.C.sub.r <D.sub.m .multidot.C.sub.o. In operation the agent dissolved in the reinforcing means acts as a secondary reservoir improving the release characteristics of the system. Specific embodiments of the invention are particularly adapted for scrotal and labial delivery of drugs such as testosterone and progesterone.
Inventor(s): Campbell; Patricia S. (Palo Alto, CA), Eckenhoff; James B. (Los Altos, CA)
Assignee: Alza Corporation (Palo Alto, CA)
Application Number:06/626,095
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 4,704,282

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Serving hundreds of leading biopharmaceutical companies globally:

Cerilliant
McKesson
Chubb
Express Scripts
Colorcon
US Department of Justice
Medtronic
Harvard Business School
Chinese Patent Office

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