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Serving leading biopharmaceutical companies globally:

Federal Trade Commission
Harvard Business School
Johnson and Johnson
Boehringer Ingelheim
Merck
McKinsey
UBS
Deloitte
McKesson
Accenture

Generated: January 19, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,696,949

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Summary for Patent: 4,696,949
Title: Novel tri-phenyl alkane and alkene derivatives and their preparation and use
Abstract:The invention provides novel compounds of the formula: ##STR1## wherein n is 0 to 4, R.sub.1 and R.sub.2, which can be the same or different are H, OH, alkoxy of 1 to 4 carbon atoms, benzyloxy or methoxymethoxy; R.sub.3 is H, OH, halogen, alkoxy of 1 to 4 carbon atoms, benzyloxy, methoxymethoxy, 2,3-dihydroxypropoxy or ##STR2## wherein m is 1 or 2, R.sub.6 and R.sub.7, which can be the same or different are H or an alkyl group of 1 to 4 carbon atoms, or ##STR3## can form an N-containing three-, four-, five- or six-membered heterocyclic ring; R.sub.4 is OH, F, Cl, Br, I, mesyloxy, tosyloxy, alkylcarbonyloxy of 1 to 4 C-atoms, formyloxy or CH.sub.2 R.sub.4 is replaced by CHO; R.sub.5 is H or OH; or R.sub.4 and R.sub.5 together form an --O-- bridge between the carbon atoms to which they are attached, and their non-toxic pharmaceutically acceptable salts and esters and mixtures thereof. Processes for the preparation of these compounds are described, and also novel pharmaceutical compositions containing them. These compounds exhibit valuable pharmacological properties as estrogenic, anti-estrogenic, and progestanic agents. They are also effective against oestrogen-dependent tumors. Certain compounds are useful as chemical intermediates for the preparation of pharmacologically active compounds of the invention.
Inventor(s): Toivola; Reijo J. (Oulu, FI), Karjalainen; Arto J. (Oulu, FI), Kurkela; Kauko O. A. (Oulu, FI), Soderwall; Marja-Liisa (Oulu, FI), Kangas; Lauri V. M. (Turki, FI), Blanco; Guillermo L. (Oulu, FI), Sunduiqst; Hannu K. (Kaarina, FI)
Assignee: Farmos Group Ltd. (Turku, FI)
Application Number:06/823,856
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Drugs Protected by US Patent 4,696,949

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 4,696,949

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8218414Jun 25, 1982

International Patents Family Members for US Patent 4,696,949

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 22064 ➤ Subscribe
Austria 383344 ➤ Subscribe
Austria A192983 ➤ Subscribe
Australia 1494683 ➤ Subscribe
Australia 556608 ➤ Subscribe
Bulgaria 60760 ➤ Subscribe
Canada 1185977 ➤ Subscribe
German Democratic Republic 230864 ➤ Subscribe
Germany 3366021 ➤ Subscribe
Denmark 165785 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

US Department of Justice
Cipla
Colorcon
Daiichi Sankyo
Mallinckrodt
Cantor Fitzgerald
Teva
Cerilliant
Dow

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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