BioPharmaceutical Business Intelligence

  • Identify first generic entrants
  • Uncover prior art in expired and abandoned patents
  • Obtain formulation and manufacturing information
➤ Start Trial

or, See Plans & Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving leading biopharmaceutical companies globally:

Cipla
UBS
Medtronic
US Department of Justice
QuintilesIMS
Deloitte
Boehringer Ingelheim
Mallinckrodt
Dow
Fuji

Generated: January 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,687,659

« Back to Dashboard

Summary for Patent: 4,687,659
Title: Diamide-DTPA-paramagnetic contrast agents for MR imaging
Abstract:Homologs of Diamide-DTPA-Paramagnetic compounds (such as diamido acetyl diethylene triamine triacetic acid) provide excellent contrast agents for magnetic resonance (MR) imaging. The magnetic dipole generated by the unpaired electron within the paramagnetic (PM) atom, causes a local reduction in the bulk magnetic field of the MR system. The resulting shorting of the T1 (spin lattice) relaxation time in the local hydrogen protons within the area of interest, causes an intense "free induction signal" and a corresponding modulation in the collected scanning data. The tissue or organ of interest appears on the MR display highlighted in white. Background tissue is displayed as darker or lower intensity greys. A surface highlighted image of the small and large intestine may be obtained by venous injection of the diamide contrast agent. The contrast agent is formed by replacing two carboxylic acids on the DTPA chelator with functional amide groups. The homologs enable the Diamide-DTPA-PM contrast agents to go into solution readily, and promote organ selectivity.
Inventor(s): Quay; Steven C. (Menlo Park, CA)
Assignee: Salutar, Inc. (Sunnyvale, CA)
Application Number:06/671,106
Patent Claim Types:
see list of patent claims
Formulation; Composition; Compound; Use;

Drugs Protected by US Patent 4,687,659

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

International Patents Family Members for US Patent 4,687,659

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Germany 3590496 ➤ Subscribe
Germany 3590578 ➤ Subscribe
European Patent Office 0200750 ➤ Subscribe
European Patent Office 0203962 ➤ Subscribe
United Kingdom 2177086 ➤ Subscribe
United Kingdom 2181428 ➤ Subscribe
United Kingdom 8613493 ➤ Subscribe
United Kingdom 8614549 ➤ Subscribe
Hong Kong 6794 ➤ Subscribe
Japan H0645632 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

For more information try a trial or see the plans and pricing

Serving leading biopharmaceutical companies globally:

McKinsey
AstraZeneca
QuintilesIMS
US Department of Justice
UBS
Healthtrust
Covington
Fish and Richardson
Novartis

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

botpot