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Serving hundreds of leading biopharmaceutical companies globally:

Chinese Patent Office
Citi
Julphar
Farmers Insurance
QuintilesIMS
Baxter
Covington
Fish and Richardson
US Department of Justice

Generated: May 21, 2018

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Details for Patent: 4,636,499

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Summary for Patent: 4,636,499
Title: Sulphenamides
Abstract:Novel compounds of the formula IIIa ##STR1## wherein R.sup.1a, R.sup.2a, R.sup.3a and R.sup.4a are the same or different and are hydrogen, an alkyl, alkoxy optionally completely or predominantly substituted by fluorine or chlorine, halogen, --CN, --CF.sub.3, --NO.sub.2, --COR, --COOR, aryl, aryloxy or arylalkoxy group, or adjacent groups R.sup.1a, R.sup.2a, R.sup.3a and R.sup.4a together with the adjacent carbon atoms in the benzimidazole ring form a 5-, 6- or 7-membered monocyclic ring or a 9-, 10- or 11-membered bicyclic ring, which rings may be saturated or unsaturated and may contain 0-3 heteroatoms selected from N and O and which rings may be optionally substituted with 1-4 substitutents selected from alkyl groups with 1-3 carbon atoms, halogen perferably F or Cl, alkylene radicals containing 4-5 carbon atoms giving spiro compounds, or two or four of these substituents together form one or two oxy groups ##STR2## whereby if R.sup.1a, R.sup.2a, R.sup.3a and R.sup.4a together with the adjacent carbon atoms in the benzimidazole ring form two rings they may be condensed with each other, R.sup.5a is hydrogen or an alkyl group, R.sup.6a is hydrogen or an alkyl group or R.sup.5a and R.sup.6a are joined together to form an alkylene chain, R.sup.7a is hydrogen, an alkyl, alkoxy, alkenyloxy, or alkynyloxy group, R.sup.8a is hydrogen or an alkyl group, or R.sup.6a and R.sup.7a, or R.sup.7a and R.sup.8a together with the adjacent carbon atoms in the pyridinium ring form a ring wherein the part constituted by R.sup.6a and R.sup.7a or R.sup.7a and R.sup.8a, is --CH.dbd.CH--CH.dbd.CH--, --O--(CH.sub.2).sub.p --, --CH.sub.2 (CH.sub.2).sub.p --, --O--CH.dbd.CH--, --NH--CH.dbd.CH--, ##STR3## or --S--(CH.sub.2).sub.p --, wherein p is 2, 3 or 4 and the O, S and N atoms always are attached to position 3 in the compound IIIa, R is an alkyl, cycloalkyl, aryl or arylalkyl group, and X.sup.- is a pharmaceutically acceptable anion, process for preparation thereof, pharmaceutical compositions containing such compounds and their use in medicine.
Inventor(s): Brandstrom; Arne E. (Gothenburg, SE), Lindberg; Per L. (Askim, SE), Wallmark; Bjorn (Molnlycke, SE)
Assignee: Aktiebolaget Hassle (Molndal, SE)
Application Number:06/739,425
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 4,636,499
Patent Claim Types:
see list of patent claims
Compound; Process; Use; Composition; Dosage form;

Drugs Protected by US Patent 4,636,499

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 4,636,499

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Sweden8403179Jun 13, 1984

International Family Members for US Patent 4,636,499

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Japan S617281 ➤ Try a Free Trial
European Patent Office 0171372 ➤ Try a Free Trial
Germany 3565406 ➤ Try a Free Trial
Japan H0696581 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Merck
Fish and Richardson
Johnson and Johnson
Queensland Health
Daiichi Sankyo
Express Scripts
US Department of Justice
Cipla
Colorcon

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