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Serving leading biopharmaceutical companies globally:

Harvard Business School
AstraZeneca
Johnson and Johnson
Deloitte
Chinese Patent Office
QuintilesIMS
Boehringer Ingelheim
Fish and Richardson
US Department of Justice
McKinsey

Generated: January 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,621,077

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Summary for Patent: 4,621,077
Title: Pharmacologically active biphosphonates, process for the preparation thereof and pharmaceutical compositions therefrom
Abstract:Biphosphonic acids of general formula I: ##STR1## in which R is a fluorine atom of a linear or branched alkyl radical containing between 1 and 5 carbon atoms, which may also be substituted by one or more amino groups of fluorine atoms or both amino groups and fluorine atoms, R' is hydroxy or fluorine, and their salts with an alkali metal, an organic base or a basic aminoacid, exhibit valuable properties in the treatment of urolithiasis or in the treatment as inhibitors of bone reabsorption. The compound 4-amino-1-hydroxybutan-1,1-biphosphonic acid is between 100 and 300 times more active than Cl.sub.2 MDP.
Inventor(s): Rosini; Sergio (Pisa, IT), Staibano; Giorgio (Pisa, IT)
Assignee: Istituto Gentili S.p.A. (Pisa, IT)
Application Number:06/618,578
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 4,621,077

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 4,621,077

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Italy20781 A/82Apr 15, 1982

International Patents Family Members for US Patent 4,621,077

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Belgium 896453 ➤ Subscribe
Switzerland 661437 ➤ Subscribe
Germany 19675047 ➤ Subscribe
Germany 3313049 ➤ Subscribe
France 2525223 ➤ Subscribe
United Kingdom 2118042 ➤ Subscribe
United Kingdom 8308791 ➤ Subscribe
Hong Kong 79390 ➤ Subscribe
Italy 1201087 ➤ Subscribe
Italy 8220781 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

Merck
QuintilesIMS
Fish and Richardson
Cantor Fitzgerald
Daiichi Sankyo
AstraZeneca
Fuji
Argus Health
Deloitte

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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