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Serving hundreds of leading biopharmaceutical companies globally:

Deloitte
Julphar
Cantor Fitzgerald
Colorcon
Daiichi Sankyo
Harvard Business School
Cerilliant
Argus Health
Fuji

Generated: April 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,621,077

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Summary for Patent: 4,621,077
Title: Pharmacologically active biphosphonates, process for the preparation thereof and pharmaceutical compositions therefrom
Abstract:Biphosphonic acids of general formula I: ##STR1## in which R is a fluorine atom of a linear or branched alkyl radical containing between 1 and 5 carbon atoms, which may also be substituted by one or more amino groups of fluorine atoms or both amino groups and fluorine atoms, R' is hydroxy or fluorine, and their salts with an alkali metal, an organic base or a basic aminoacid, exhibit valuable properties in the treatment of urolithiasis or in the treatment as inhibitors of bone reabsorption. The compound 4-amino-1-hydroxybutan-1,1-biphosphonic acid is between 100 and 300 times more active than Cl.sub.2 MDP.
Inventor(s): Rosini; Sergio (Pisa, IT), Staibano; Giorgio (Pisa, IT)
Assignee: Istituto Gentili S.p.A. (Pisa, IT)
Application Number:06/618,578
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 4,621,077

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 4,621,077

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Italy20781 A/82Apr 15, 1982

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Serving hundreds of leading biopharmaceutical companies globally:

Fuji
Farmers Insurance
Colorcon
Daiichi Sankyo
Baxter
Fish and Richardson
Cantor Fitzgerald
Queensland Health
Covington

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