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Serving hundreds of leading biopharmaceutical companies globally:

Medtronic
Covington
Daiichi Sankyo
US Department of Justice
Federal Trade Commission
Express Scripts
Julphar
Cantor Fitzgerald
US Army

Generated: June 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,621,077

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Summary for Patent: 4,621,077
Title: Pharmacologically active biphosphonates, process for the preparation thereof and pharmaceutical compositions therefrom
Abstract:Biphosphonic acids of general formula I: ##STR1## in which R is a fluorine atom of a linear or branched alkyl radical containing between 1 and 5 carbon atoms, which may also be substituted by one or more amino groups of fluorine atoms or both amino groups and fluorine atoms, R' is hydroxy or fluorine, and their salts with an alkali metal, an organic base or a basic aminoacid, exhibit valuable properties in the treatment of urolithiasis or in the treatment as inhibitors of bone reabsorption. The compound 4-amino-1-hydroxybutan-1,1-biphosphonic acid is between 100 and 300 times more active than Cl.sub.2 MDP.
Inventor(s): Rosini; Sergio (Pisa, IT), Staibano; Giorgio (Pisa, IT)
Assignee: Istituto Gentili S.p.A. (Pisa, IT)
Application Number:06/618,578
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 4,621,077
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 4,621,077

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 4,621,077

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Italy20781 A/82Apr 15, 1982

International Family Members for US Patent 4,621,077

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Belgium 896453 ➤ Try a Free Trial
Switzerland 661437 ➤ Try a Free Trial
Germany 19675047 ➤ Try a Free Trial
Germany 3313049 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Express Scripts
Cerilliant
Cipla
Daiichi Sankyo
Covington
Boehringer Ingelheim
McKesson
Chubb
Mallinckrodt

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