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|Title:||Carbazolyl-(4)-oxypropanolamine compounds and therapeutic compositions|
|Abstract:||Carbazolyl-(4)-oxypropanolamine compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, lower alkanoyl or aroyl; R.sub.2 is hydrogen, lower alkyl or arylalkyl; R.sub.3 is hydrogen or lower alkyl; R.sub.4 is hydrogen or lower alkyl, or when X is oxygen, R.sub.4 together with R.sub.5 can represent --CH.sub.2 --O--; X is a valency bond, --CH.sub.2 --, oxygen or sulfur; Ar is mono- or bicyclic aryl or pyridyl; R.sub.5 and R.sub.6 are individually selected from hydrogen, halogen, hydroxyl, lower alkyl, aminocarbonyl, lower alkoxy, aralkyloxy, lower alkylthio, lower alkylsulphinyl or lower alkylsulphonyl; R.sub.5 and R.sub.6 together can represent methylenedioxy; and the salts thereof with physiologically acceptable acids are outstandingly effective in the treatment and prophylaxis of circulatory and cardiac diseases, e.g., hypertension and angina pectoris.|
|Inventor(s):||Wiedemann; Fritz (Weinheim-L/u/ tzelsachsen, DE), Kampe; Wolfgang (Heddesheim, DE), Thiel; Max (Mannheim, DE), Sponer; Gisbert (Hemsbach, DE), Roesch; Egon (Mannheim, DE), Dietmann; Karl (Mannheim-Vogelstang, DE)|
|Assignee:||Boehringer Mannheim GmbH (Mannheim-Waldhof, DE)|
Patent Claim Types:|
see list of patent claims
|Compound; Use; Composition;|
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|Germany||2815926||Apr 13, 1978|
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|Hong Kong||2385||► subscribe|
| This preview shows a limited data set|
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