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Details for Patent: 4,447,424

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Summary for Patent: 4,447,424

Title: Steroid derivatives
Abstract:Novel 19-nor steroids and 19-nor-D-homo-steroids of the formula ##STR1## wherein R.sub.1 is an organic radical of 1 to 18 carbon atoms containing at least one atom selected from the group consisting of nitrogen, phosphorous and silicon with the atom immediately adjacent to the 11-carbon atom being carbon, R.sub.2 is a hydrocarbon of 1 to 8 carbon atoms, X is selected from the group consisting of a pentagonal ring and a hexagonal ring optionally substituted and optionally containing a double bond, B and C together form a double bond or an epoxy group, the C.dbd.A group at position 3 is selected from the group consisting of C--O, ketal, which may be open or closed ##STR2## --C.dbd.NOH, --C--NOAlK.sub.3 and C--CH.sub.2, AlK.sub.1, AlK.sub.2 and AlK.sub.3 are selected from the group consisting of alkyl of 1 to 8 carbon atoms and aralkyl of 7 to 15 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having anti-glucocorticoid activity and a process for their preparation.
Inventor(s): Teutsch; Jean G. (Pantin, FR), Costerousse; Germain (Saint-Maurice, FR), Philibert; Daniel (La Varenne Saint Hilaire, FR), Deraedt; Roger (Pavillons sous Bois, FR)
Assignee: Roussel Uclaf (Paris, FR)
Application Number:06/386,967
Patent Claim Types:
see list of patent claims
Composition; Compound; Use; Delivery;

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Foreign Priority and PCT Information for Patent: 4,447,424

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
France81 00272Jan 09, 1981

International Patent Family for Patent: 4,447,424

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Germany3380628<disabled in preview>
Germany3262580<disabled in preview>
Germany3273985<disabled in preview>
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
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