Last Updated: November 8, 2026

Details for Patent: 4,436,738

Name: Drug Patent Intelligence for US Patent 4436738
Creator: DrugPatentWatch
License: https://www.drugpatentwatch.com/terms.php

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Summary for Patent: 4,436,738

Title:	Stabilized estradiol cream composition
Abstract:	Loss of potency of estradiol cream compositions found to be due to unexpected oxidation of estradiol. Improved cream composition comprises 1% or less 17β-estradiol in the presence of stabilizing members selected from phenolic-type antioxidants, metal chelating agents, and suspending agents.
Inventor(s):	Robert J. Bequette, Linda G. Hobbs, Joseph A. Scott
Assignee:	Warner Chilcott Co LLC
Application Number:	US06/358,068
Patent Claim Types: see list of patent claims	Composition; Formulation; Compound;

Drugs Protected by US Patent 4,436,738

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>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

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