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Last Updated: March 28, 2024

Details for Patent: 4,360,511


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Summary for Patent: 4,360,511
Title: Amines useful as brain imaging agents
Abstract:Certain radioiodine containing amines useful as brain imaging agents are disclosed. The compounds of the invention are represented by the formula ##STR1## wherein I is a radioisotope of iodine with I-123 being preferred, R is lower alkyl or halogen, R.sub.1 and R.sub.2 are the same or different and are selected from the group consisting of hydrogen and lower alkyl, R.sub.3 and R.sub.4 are the same or different and are selected from the group consisting of hydrogen, alkyl, aryl, substituted aryl, aralkyl, substituted aralkyl and substituted carbamoyl methyl or R.sub.3 and R.sub.4 taken together with the nitrogen to which they are attached form a 5- or 6-membered ring which may be substituted with one or more lower alkyl groups, x is 0 to 4, y is 0 to 3 and z is 0 or 1 and pharmaceutically acceptable acid addition salts thereof.
Inventor(s): Baldwin; Ronald M. (San Francisco, CA), Lin; Tz-Hong (Fremont, CA), Winchell; Harry S. (Lafayette, CA)
Assignee: Medi-Physics, Inc. (Emeryville, CA)
Application Number:06/161,097
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Drugs Protected by US Patent 4,360,511

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 4,360,511

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Germany 2965469 ⤷  Try a Trial
European Patent Office 0011858 ⤷  Try a Trial
Hong Kong 65586 ⤷  Try a Trial
Japan S5573640 ⤷  Try a Trial
Japan S5932457 ⤷  Try a Trial
Singapore 23186 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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