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Serving leading biopharmaceutical companies globally:

Cantor Fitzgerald
Fish and Richardson
US Army
Chinese Patent Office

Generated: December 10, 2017

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Details for Patent: 4,277,479

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Summary for Patent: 4,277,479

Title: Tetrazolylalkoxycarbostyril derivatives and pharmaceutical compositions containing them
Abstract:Novel tetrazolylalkoxycarbostyril derivative of the formula (I): ##STR1## wherein R.sup.1 is a hydrogen atom, a lower alkyl group, a low alkenyl group, a lower alkanoyl group, a benzoyl group or phenylalkyl group; R.sup.2 is a hydrogen atom, a lower alkyl group or a group of the formula ##STR2## R.sup.3 is a lower alkyl group, a cycloalkyl group, a cycloalkylalkyl group, a phenyl group or a phenylalkyl group; A is a lower alkylene group; the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton is either single or double bond; and the substituted position of a group of the formula, ##STR3## in the carbostyril skeleton is either 4-, 5-, 6-, 7- or 8-position provided that the only one such group of the formula can be substituted in the whole carbostyril skeleton, thus when R.sup.2 in 4-position is a group of the formula ##STR4## then 5-, 6-, 7- or 8-position will have no such substituted group; furthermore, the phenyl group in the above-mentioned benzoyl group, phenylalkyl group or phenyl group may have substituted group(s). The above-mentioned novel tetrazolylalkoxycarbostyril derivatives have pharmacological activities such as platelet aggregation inhibitory action, antiinflammatory action, antiulcer action, vasodilatory action and phosphodiesterase inhibitory action and are useful as anti-thrombosis agent, cerebral blood flow improving agent, antiinflammatory agent, antiulcer agent, anti-hypertensive agent and anti-asthmatic agent.
Inventor(s): Nishi; Takao (Tokushima, JP), Nakagawa; Kazuyuki (Tokushima, JP)
Assignee: Otsuka Pharmaceutical Co., Ltd. (Tokyo, JP)
Application Number:06/070,710
Patent Claim Types:
see list of patent claims
Compound; Composition;

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Foreign Priority and PCT Information for Patent: 4,277,479

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan53/107869Sep 01, 1978

International Patent Family for Patent: 4,277,479

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina229342► Subscribe
Austria364363► Subscribe
AustriaA584579► Subscribe
Australia5039779► Subscribe
Australia538410► Subscribe
Belgium878548► Subscribe
Canada1139761► Subscribe
Switzerland641799► Subscribe
Germany2934747► Subscribe
Denmark158788► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Express Scripts
Chinese Patent Office
Fish and Richardson
Boehringer Ingelheim

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