Details for Patent: 4,264,573
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Summary for Patent: 4,264,573
Title: | Pharmaceutical formulation for slow release via controlled surface erosion |
Abstract: | A pharmaceutical composition in tablet form for oral administration comprises: (a) 30-90% by weight of an active ingredient having a water solubility (20.degree. C.) of about 1/10-1/500 (w/w); (b) 1-40% by weight of an excipient which is pharmaceutically acceptable in oral tablets and which has a water solubility (20.degree. C.) of about 1/1-1/20 (w/w); (c) 0-20% by weight of a binder which is pharmaceutically acceptable in oral tablets; (d) 0-50% by weight of an excipient which is pharmaceutically acceptable in oral tablets and which has a water solubility (20.degree. C.) of about 1/1-1/5 (w/w); (e) 0.5-5% by weight of a die wall lubricant pharmaceutically acceptable in oral tablets; (f) 0-5% by weight of a surface active agent pharmaceutically acceptable in oral tablets; and (g) 0-1.0% by weight of a disintegration agent pharmaceutically acceptable in oral tablets; whereby the active ingredient has a slow in vivo release rate due to controlled surface erosion of the tablet. |
Inventor(s): | Powell; David R. (Baudette, MN), Patel; Vithal K. (Baudette, MN) |
Assignee: | Rowell Laboratories, Inc. (Baudette, MN) |
Application Number: | 06/040,789 |
Patent Claim Types: see list of patent claims | Composition; Dosage form; |
Drugs Protected by US Patent 4,264,573
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |