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Generated: January 16, 2018

DrugPatentWatch Database Preview

Details for Patent: 4,201,211

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Summary for Patent: 4,201,211
Title: Therapeutic system for administering clonidine transdermally
Abstract:Therapeutic system in the form of a skin patch that administers clonidine transdermally in an initial priming dose of 10 to 300 mcg/cm.sup.2 of skin that brings the concentration of clonidine in the blood to a level sufficient to elicit alpha-adrenergic stimulation without intolerable side effects, followed by a substantially constant continuous dosage in the range of 0.1 to 100 mcg/hr that maintains said level. The system is a four-layer laminate of, from the top: a protective backing; a gelled, mineral oil-polyisobutene-clonidine reservoir lamina that is the source of the clonidine for the continuous constant dosage; a microporous membrane that controls the constant dosage rate; and a gelled, mineral oil-polyisobutene-clonidine contact adhesive layer that is the source of the clonidine for the priming dose and the means by which the system is attached to the skin.
Inventor(s): Chandrasekaran; Santosh K. (Palo Alto, CA), Darda; Siegfried (Ingelheim am Rhein, DE), Michaels; Alan S. (Atherton, CA), Cleary; Gary W. (Palo Alto, CA)
Assignee: ALZA Corporation (Palo Alto, CA) Boehringer Ingelheim GmbH (Ingelheim am Rhein, DE)
Application Number:05/815,033
Patent Claim Types:
see list of patent claims
Composition;

Drugs Protected by US Patent 4,201,211

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 4,201,211

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 218037 ➤ Subscribe
Austria A905877 ➤ Subscribe
Austria 362884 ➤ Subscribe
Australia 512328 ➤ Subscribe
Australia 2846277 ➤ Subscribe
Belgium 862585 ➤ Subscribe
Bulgaria 29866 ➤ Subscribe
Canada 1089362 ➤ Subscribe
Switzerland 646876 ➤ Subscribe
Czechoslovakia 216917 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

Deloitte
Fish and Richardson
Teva
Cipla
Novartis
Mallinckrodt
Argus Health
Cerilliant
Merck

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