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Serving leading biopharmaceutical companies globally:

Fish and Richardson
Johnson and Johnson
Federal Trade Commission

Generated: October 22, 2017

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Details for Patent: 4,201,211

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Summary for Patent: 4,201,211

Title: Therapeutic system for administering clonidine transdermally
Abstract:Therapeutic system in the form of a skin patch that administers clonidine transdermally in an initial priming dose of 10 to 300 mcg/cm.sup.2 of skin that brings the concentration of clonidine in the blood to a level sufficient to elicit alpha-adrenergic stimulation without intolerable side effects, followed by a substantially constant continuous dosage in the range of 0.1 to 100 mcg/hr that maintains said level. The system is a four-layer laminate of, from the top: a protective backing; a gelled, mineral oil-polyisobutene-clonidine reservoir lamina that is the source of the clonidine for the continuous constant dosage; a microporous membrane that controls the constant dosage rate; and a gelled, mineral oil-polyisobutene-clonidine contact adhesive layer that is the source of the clonidine for the priming dose and the means by which the system is attached to the skin.
Inventor(s): Chandrasekaran; Santosh K. (Palo Alto, CA), Darda; Siegfried (Ingelheim am Rhein, DE), Michaels; Alan S. (Atherton, CA), Cleary; Gary W. (Palo Alto, CA)
Assignee: ALZA Corporation (Palo Alto, CA) Boehringer Ingelheim GmbH (Ingelheim am Rhein, DE)
Application Number:05/815,033
Patent Claim Types:
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International Patent Family for Patent: 4,201,211

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina218037► Subscribe
AustriaA905877► Subscribe
Austria362884► Subscribe
Australia512328► Subscribe
Australia2846277► Subscribe
Belgium862585► Subscribe
Bulgaria29866► Subscribe
Canada1089362► Subscribe
Switzerland646876► Subscribe
Czechoslovakia216917► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Harvard Business School
Cantor Fitzgerald
Fish and Richardson

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