|Title:||7.alpha.-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their manufacture, their use as anti-inflammatory agents, and pharmaceutical formulations useful therefor|
|Abstract:||Novel 3,20-dioxo-7.alpha.-halogeno-1,4-pregnadienes are described and their use as anti-inflammatory agents. Preferred are 7.alpha.-bromo- and 7.alpha.-chloro- derivatives, particularly 7.alpha.-bromo- and 7.alpha.-chloro-1,4-pregnadienes-11.beta.,17.alpha.,21-triol-3,20-dione 17,21-dihydrocarboncarboxylates, the 16-methyl and 16-methylene derivatives thereof being particularly valuable as topical anti-inflammatory agents.|
|Inventor(s):||Green; Michael J. (Kendall Park, NJ), Shue; Ho-Jane (Belleville, NJ)|
|Assignee:||Schering Corporation (Kenilworth, NJ)|
Patent Claim Types:|
see list of patent claims
|Compound; Use; Composition;|
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