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Serving leading biopharmaceutical companies globally:

Express Scripts
Farmers Insurance
Daiichi Sankyo
Fish and Richardson

Generated: December 16, 2017

DrugPatentWatch Database Preview

Details for Patent: 4,089,969

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Summary for Patent: 4,089,969

Title: 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
Abstract:Novel 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid compounds represented by the formula ##STR1## and the pharmaceutically acceptable, non-toxic esters and salts thereof, wherein R is hydrogen or a lower alkyl group containing from 1 to 4 carbon atoms and R.sup.1 is hydrogen, a lower alkyl group having from 1 to 4 carbon atoms, a lower alkoxy group of 1 to 4 carbon atoms, chloro, fluoro or bromo, the R.sup.1 substitution being at the ortho, meta or para positions of the aroyl group and process for the production of such compounds; 5-p-toluoyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid is representative of the class. These compounds, as the racemic mixture or the (1)-isomer, are useful as anti-inflammatory, analgesic and antipyretic agents and as smooth muscle relaxants.
Inventor(s): Muchowski; Joseph M. (Mexico City, MX), Kluge; Arthur F. (Los Altos, CA)
Assignee: Syntex (U.S.A.) Inc. (Palo Alto, CA)
Application Number:05/771,286
Patent Claim Types:
see list of patent claims
Compound; Use; Composition; Delivery;

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International Patent Family for Patent: 4,089,969

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina224997► Subscribe
Austria363465► Subscribe
Austria364844► Subscribe
Austria369003► Subscribe
AustriaA402479► Subscribe
AustriaA509077► Subscribe
AustriaA573780► Subscribe
Australia2697577► Subscribe
Australia513384► Subscribe
Belgium856681► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Fish and Richardson
Federal Trade Commission

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