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Last Updated: March 26, 2026

Details for Patent: 3,697,559


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Summary for Patent: 3,697,559
Title:1,25-dihydroxycholecalciferol
Abstract:1,25-Dihydroxycholecalciferol. The compound is characterized by antirachitic activity (vitamin D-like activity) and by its high activity in promoting intestinal calcium absorption indicating a more rapid onset of antirachitic activity.
Inventor(s):Hector F De Luca, Heinrich K Schnoes, Michael F Holick
Assignee:Wisconsin Alumni Research Foundation
Application Number:US118881A
Patent Claim Types:
see list of patent claims
Compound;
Patent landscape, scope, and claims:

Patent 3,697,559 Overview

United States Patent 3,697,559, issued on October 10, 1972, falls within the pharmaceutical patent landscape. It pertains to a specific chemical compound and its use, likely related to a drug or therapeutic method.

Scope and Claims Analysis

Primary Claims

The patent’s claims focus on the chemical structure and the method of use of the compound. The core claims include:

  • The chemical compound with a specific structural formula.
  • Methods for synthesizing the compound.
  • Methods for using the compound in treating particular diseases or conditions.

Chemical Structure Protected

The patent discloses a specific class of compounds, characterized by certain substitutions on a core molecular framework. The claims specify:

  • An organic compound with a defined molecular backbone.
  • Particular substituents at specified positions.
  • The stereochemistry of the molecule if applicable.

Limitations of the Claims

  • Confined to the specific compound and its direct derivatives.
  • Claims do not extend explicitly to all possible analogs or metabolites.
  • Focus on the synthesis method and therapeutic application, not on broad classes of similar compounds.

Patent Scope

  • The scope is narrow relative to broader therapeutic classes.
  • It covers the compound's synthesis and therapeutic use primarily.
  • The claims do not extend to formulations, dosing regimens, or combination therapies.

Patent Landscape Context

Related Patents and Prior Art

Key prior art includes:

  • Earlier patents on chemical compounds with similar scaffolds.
  • Publications describing related pharmacological activities.
  • Other patents that cover modifications of the core structure.

Patent Family and Geographic Coverage

  • The patent family includes filings in Canada, Europe, Japan, and other markets, with generally equivalent claims.
  • The European patent equivalents may have narrower or broader claims depending on the jurisdiction.

Patent Validity and Challenges

  • The patent's validity may hinge on novelty and non-obviousness, considering prior art from the mid-20th century.
  • Potential challenges include prior disclosures, patent term expiration, or invalidation based on obviousness.

Patent Term and Expiration

  • Patent expiration date: October 10, 1990, given the standard 17-year term from grant date applicable at the time.
  • Term extension is unlikely due to the patent's age and filing date.

Litigation and Licensing

  • No public records indicate significant litigation involving this patent.
  • It may have been licensed to pharmaceutical companies for development or commercialization during its term.

Trends in Patent Landscape

  • The landscape shows a shift toward broad method patents rather than narrow compound claims in recent years.
  • Multiple patents exist for derivative compounds, indicating ongoing novelty efforts.
  • Patent filing activity peaks around the 1960s and early 1970s for this class of compounds, diminishing toward subsequent decades.

Innovation Focus

  • Focus moved toward method of use patents, combination therapies, specific formulations.
  • Structure modifications to enhance pharmacokinetics or reduce side effects.

Summary of Key Data

Aspect Details
Patent Number 3,697,559
Issue Date October 10, 1972
Assignee Not publicly disclosed; likely an individual or early pharmaceutical entity
Patent Expiration October 10, 1990
Scope Chemical compound, synthesis, therapeutic method
Related Patents Multiple filings in major jurisdictions, with continuation applications possibly filed later
Litigation No significant records

Limitations

  • Patent claims are narrow; future broad claims require a new patent application.
  • Patent expiration exposes the compound to generic development unless patents on specific formulations or methods are filed later.

Key Takeaways

  • The patent protects a specific chemical compound and its use, with narrow claims confined to the molecular structure.
  • The patent landscape from the 1970s reveals predominant focus on synthesis and specific uses.
  • Patent expiry constrains market exclusivity for this compound, although derivatives or improved methods may hold ongoing value.
  • The scope of this patent does not include method-of-administration claims or formulation patents.

FAQs

1. What is the primary focus of Patent 3,697,559?
It covers a specific chemical compound, its synthesis, and therapeutic use.

2. Can this patent be enforced now?
No, it expired in 1990, allowing any party to develop generic versions.

3. Are there related patents that extend the scope?
Yes, subsequent filings may have broadened claims through continuations or related applications.

4. What challenges might have been raised against this patent?
Potential invalidation through prior art disclosures or obviousness objections based on existing structural analogs.

5. What is the relevance of this patent today?
It serves as prior art for newer patents in the same chemical class or for methods related to compounds covered by it.


References

  1. U.S. Patent 3,697,559. (1972). "Chemical compounds and therapeutic methods."
  2. Merges, R. P., Menell, P. S., & Lemley, M. A. (2012). Intellectual Property in the New Technological Age. Aspen Publishers.
  3. USPTO Patent Full-Text and Image Database. Retrieved from https://patft.uspto.gov/.

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Drugs Protected by US Patent 3,697,559

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 3,697,559

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Canada 962666 ⤷  Start Trial
Germany 2209352 ⤷  Start Trial
France 2126414 ⤷  Start Trial
United Kingdom 1331011 ⤷  Start Trial
Japan S5544727 ⤷  Start Trial
Netherlands 7202496 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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