Details for Patent: 12,370,179
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Which drugs does patent 12,370,179 protect, and when does it expire?
Patent 12,370,179 protects MYQORZO and is included in one NDA.
This patent has twenty-five patent family members in twenty-three countries.
Summary for Patent: 12,370,179
| Title: | Methods for treating hypertrophic cardiomyopathy |
| Abstract: | Methods for treating obstructive hypertrophic cardiomyopathy are described herein. The treatment methods include the administration of a cardiac myosin inhibitor (CK-3773274, also referred to as CK-274 or aficamten) and may include titrating an administrated daily dose based on one or more components of an echocardiogram. The daily dose may be increased, maintained, decreased, or terminated, based on the echocardiogram. |
| Inventor(s): | Fady Malik, Stuart Kupfer, Stephen B. Heitner, Laura Ann Robertson, Lixin Meng, Anna Osmukhina, Qi Wohltman |
| Assignee: | Cytokinetics Inc |
| Application Number: | US18/909,401 |
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Patent Claim Types: see list of patent claims | Use; Device; |
Drugs Protected by US Patent 12,370,179
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cytokinetics | MYQORZO | aficamten | TABLET;ORAL | 219083-001 | Dec 19, 2025 | RX | Yes | Yes | 12,370,179 | ⤷ Start Trial | TREATMENT OF ADULTS WITH SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (OHCM) TO IMPROVE FUNCTIONAL CAPACITY AND SYMPTOMS | ⤷ Start Trial | ||||
| Cytokinetics | MYQORZO | aficamten | TABLET;ORAL | 219083-002 | Dec 19, 2025 | RX | Yes | No | 12,370,179 | ⤷ Start Trial | TREATMENT OF ADULTS WITH SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (OHCM) TO IMPROVE FUNCTIONAL CAPACITY AND SYMPTOMS | ⤷ Start Trial | ||||
| Cytokinetics | MYQORZO | aficamten | TABLET;ORAL | 219083-003 | Dec 19, 2025 | RX | Yes | No | 12,370,179 | ⤷ Start Trial | TREATMENT OF ADULTS WITH SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (OHCM) TO IMPROVE FUNCTIONAL CAPACITY AND SYMPTOMS | ⤷ Start Trial | ||||
| Cytokinetics | MYQORZO | aficamten | TABLET;ORAL | 219083-004 | Dec 19, 2025 | RX | Yes | No | 12,370,179 | ⤷ Start Trial | TREATMENT OF ADULTS WITH SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (OHCM) TO IMPROVE FUNCTIONAL CAPACITY AND SYMPTOMS | ⤷ Start Trial | ||||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 12,370,179
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Argentina | 126472 | ⤷ Start Trial | |||
| Australia | 2022312506 | ⤷ Start Trial | |||
| Canada | 3225787 | ⤷ Start Trial | |||
| Chile | 2024000090 | ⤷ Start Trial | |||
| Chile | 2024001945 | ⤷ Start Trial | |||
| China | 117794535 | ⤷ Start Trial | |||
| Denmark | 4370116 | ⤷ Start Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
