Last Updated: October 1, 2026

Details for Patent: 12,370,179


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Which drugs does patent 12,370,179 protect, and when does it expire?

Patent 12,370,179 protects MYQORZO and is included in one NDA.

This patent has twenty-five patent family members in twenty-three countries.

Summary for Patent: 12,370,179
Title:Methods for treating hypertrophic cardiomyopathy
Abstract:Methods for treating obstructive hypertrophic cardiomyopathy are described herein. The treatment methods include the administration of a cardiac myosin inhibitor (CK-3773274, also referred to as CK-274 or aficamten) and may include titrating an administrated daily dose based on one or more components of an echocardiogram. The daily dose may be increased, maintained, decreased, or terminated, based on the echocardiogram.
Inventor(s):Fady Malik, Stuart Kupfer, Stephen B. Heitner, Laura Ann Robertson, Lixin Meng, Anna Osmukhina, Qi Wohltman
Assignee: Cytokinetics Inc
Application Number:US18/909,401
Patent Claim Types:
see list of patent claims
Use; Device;

Drugs Protected by US Patent 12,370,179

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Cytokinetics MYQORZO aficamten TABLET;ORAL 219083-001 Dec 19, 2025 RX Yes Yes 12,370,179 ⤷  Start Trial TREATMENT OF ADULTS WITH SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (OHCM) TO IMPROVE FUNCTIONAL CAPACITY AND SYMPTOMS ⤷  Start Trial
Cytokinetics MYQORZO aficamten TABLET;ORAL 219083-002 Dec 19, 2025 RX Yes No 12,370,179 ⤷  Start Trial TREATMENT OF ADULTS WITH SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (OHCM) TO IMPROVE FUNCTIONAL CAPACITY AND SYMPTOMS ⤷  Start Trial
Cytokinetics MYQORZO aficamten TABLET;ORAL 219083-003 Dec 19, 2025 RX Yes No 12,370,179 ⤷  Start Trial TREATMENT OF ADULTS WITH SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (OHCM) TO IMPROVE FUNCTIONAL CAPACITY AND SYMPTOMS ⤷  Start Trial
Cytokinetics MYQORZO aficamten TABLET;ORAL 219083-004 Dec 19, 2025 RX Yes No 12,370,179 ⤷  Start Trial TREATMENT OF ADULTS WITH SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (OHCM) TO IMPROVE FUNCTIONAL CAPACITY AND SYMPTOMS ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 12,370,179

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 126472 ⤷  Start Trial
Australia 2022312506 ⤷  Start Trial
Canada 3225787 ⤷  Start Trial
Chile 2024000090 ⤷  Start Trial
Chile 2024001945 ⤷  Start Trial
China 117794535 ⤷  Start Trial
Denmark 4370116 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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