Details for Patent: 12,257,252
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Which drugs does patent 12,257,252 protect, and when does it expire?
Patent 12,257,252 protects SEPHIENCE and is included in one NDA.
This patent has twenty-seven patent family members in twenty-one countries.
Summary for Patent: 12,257,252
| Title: | Compositions and methods for increasing tetrahydrobiopterin plasma exposure |
| Abstract: | The present invention features compositions including sepiapterin, or a pharmaceutically acceptable salt thereof, and methods for the treatment of BH4-related disorders. In some embodiments, these compositions and methods result in an increase in plasma exposure of BH4. |
| Inventor(s): | Neil Smith, Jonathan Reis |
| Assignee: | PTC Therapeutics MP Inc |
| Application Number: | US17/059,632 |
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Patent Claim Types: see list of patent claims | Use; |
Drugs Protected by US Patent 12,257,252
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ptc Therap | SEPHIENCE | sepiapterin | POWDER;ORAL | 219666-002 | Jul 28, 2025 | RX | Yes | Yes | ⤷ Start Trial | ⤷ Start Trial | METHOD OF TREATING HYPERPHENYLALANINEMIA (HPA) IN ADULT AND PEDIATRIC PATIENTS WITH SEPIAPTERIN-RESPONSIVE PHENYLKETONURIA (PKU) BY ADMINISTERING SEPIAPTERIN WITH FOOD | ⤷ Start Trial | ||||
| Ptc Therap | SEPHIENCE | sepiapterin | POWDER;ORAL | 219666-001 | Jul 28, 2025 | RX | Yes | No | ⤷ Start Trial | ⤷ Start Trial | METHOD OF TREATING HYPERPHENYLALANINEMIA (HPA) IN ADULT AND PEDIATRIC PATIENTS WITH SEPIAPTERIN-RESPONSIVE PHENYLKETONURIA (PKU) BY ADMINISTERING SEPIAPTERIN WITH FOOD | ⤷ Start Trial | ||||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 12,257,252
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| European Patent Office | 3801534 | ⤷ Start Trial | 301382 | Netherlands | ⤷ Start Trial |
| European Patent Office | 3801534 | ⤷ Start Trial | CA 2026 00028 | Denmark | ⤷ Start Trial |
| European Patent Office | 3801534 | ⤷ Start Trial | PA2026521 | Lithuania | ⤷ Start Trial |
| European Patent Office | 3801534 | ⤷ Start Trial | LUC50053 | Luxembourg | ⤷ Start Trial |
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
