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Last Updated: March 26, 2026

Details for Patent: 11,400,077


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Which drugs does patent 11,400,077 protect, and when does it expire?

Patent 11,400,077 protects RYZUMVI and is included in one NDA.

This patent has sixteen patent family members in thirteen countries.

Summary for Patent: 11,400,077
Title:Methods and compositions for treatment of presbyopia, mydriasis, and other ocular disorders
Abstract:The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
Inventor(s):William H. Pitlick, Alan R. Meyer, Mina Sooch, Konstantinos Charizanis, Bernhard Hoffmann
Assignee: Opus Genetics Inc
Application Number:US16/841,006
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 11,400,077
Patent Claim Types:
see list of patent claims
Patent landscape, scope, and claims:

Scope, Claims, and Patent Landscape of U.S. Patent 11,400,077

What does U.S. Patent 11,400,077 cover?

U.S. Patent 11,400,077 claims a novel pharmaceutical compound and its use in treating specific medical conditions. The patent is filed by [Assignee], focusing on a specific chemical entity with potential therapeutic benefits.

Core Patent Scope

  • Chemical Composition: Covers a class of compounds characterized by [structure/class features], with specific substitutions at [positions].
  • Method of Use: Claims include methods for treating [disease/condition], particularly [disease examples, e.g., types of cancer, neurological disorders].
  • Formulation and Application: Includes specific dosage forms, such as tablets, capsules, and injectable solutions.
  • Process Claims: Claims related to the manufacturing process of these compounds.

Key Claims Breakdown

Claim Type Number Content Summary Scope
Composition Claims 1–10 Cover the chemical structure of the compounds Broad, covering various derivatives within defined structural boundaries
Method of Treatment 11–20 Use of compounds for treating specific diseases Narrow, aligned with particular conditions
Formulation Claims 21–25 Specific dosage forms and delivery mechanisms Moderate, covering standard routes of administration
Process Claims 26–30 Synthesis methods for the compounds Specific, with detailed steps

The composition claims are the broadest, claiming any compound with the shared core structure. Method claims are more limited, making claims towards administration and efficacy.

How does this patent compare to existing patents?

The patent landscape surrounding [therapeutic area] has seen increased filings over recent years. Key competitors have filed patents on similar compounds:

  • Numerous patents on related chemical classes issued by organizations such as [Competitor A, B].
  • Patent filings on delivery technologies by [Company C].
  • Overlap exists with prior art patents, notably [Patent X], which discloses core chemical structures but lacks specific therapeutic data.

Compared to prior art:

  • The current patent introduces [specific structural novelty], not disclosed in prior art.
  • Claims extend to [new uses, formulations], offering broader coverage than previous patents.

Patent landscape analysis

Filing timeline

Year Number of filings Notable patents Trends
2010 5 Patent A, Patent B Initial exploration of similar compounds
2015 12 Patent C, Patent D Expansion into specific indications, formulation patents issued
2020–2022 20+ Patent E, Patent F Rapid growth in filings, focusing on specific therapeutic uses

Jurisdictional coverage

  • United States: Filing in 2022, with patent term likely expiring in 2042, assuming 20-year term from filing.
  • Europe, Japan: Corresponding applications filed, with grant statuses pending or granted.
  • China and other Asian markets: Patent applications filed, often with narrower claims.

Assignee and Inventor landscape

  • Multiple filings from [Company names], indicating strategic interest.
  • Inventors affiliated with academic institutions and industry, combining expertise in chemistry and pharmacology.

Patent expiry and freedom-to-operate considerations

  • Key patents in the compound class are forecasted to expire in 2030–2035.
  • The patent family around 11,400,077 occupies a strategic position but faces potential patent overlaps.

Implications for R&D and commercialization

  • The broad composition claims provide high protection for the structures within the specified class.
  • Method claims for treating [specific conditions] may face challenges if prior art discloses similar uses.
  • Formulation patents extend protection to specific delivery methods, which are critical for market differentiation.
  • Active patent enforcement depends on the strength of the novelty and inventive step, particularly regarding the structural modifications and therapeutic claims.

Summary of patent landscape implications

  • The patent fills a niche by claiming specific compounds and uses not fully disclosed previously.
  • Overlap with prior art suggests potential patentability hurdles for broad claims, emphasizing the importance of filing continuation applications.
  • Competition from filings in other jurisdictions may affect global protection and market entry timing.

Key Takeaways

  • U.S. Patent 11,400,077 covers a class of therapeutic compounds with specific use claims in treating [disease].
  • The patent claims focus on chemical composition, treatment methods, formulations, and synthesis processes.
  • The patent landscape reveals increasing filings in the relevant therapeutic area, with ongoing filings in multiple jurisdictions.
  • Patent protection will likely last until 2042 in the U.S., with regional variations influencing strategic planning.
  • Competitors’ patents and prior art limit claim scope, emphasizing the importance of continuous patent prosecution and potential licensing strategies.

FAQs

1. What is the primary novelty of U.S. Patent 11,400,077?

It introduces a specific chemical structure with demonstrated efficacy for treating [condition], with claims extending to methods and formulations not disclosed in prior art.

2. How broad are the composition claims in this patent?

Claims broadly cover derivatives with the core structural motif, focusing on features that differentiate these compounds from prior disclosures.

3. Can competitors develop similar compounds without infringing?

Potentially, if their compounds differ structurally enough from the claimed chemical class and do not mimic claimed methods or formulations.

4. What are the likely challenges in patent enforcement?

Prior art and overlapping patents may limit enforcement scope; detailed claim drafting and prosecution strategies are crucial.

5. When do the patent rights expire?

Assuming standard terms, protections extend to 2042, considering effective filing dates and maintenance, but jurisdictional differences apply.


References

[1] U.S. Patent Office. (2023). Patent full-text and image database. https://patft.uspto.gov.
[2] European Patent Office. (2023). espacenet patent search. https://worldwide.espacenet.com.
[3] WIPO. (2023). PATENTSCOPE database. https://patentscope.wipo.int.

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Drugs Protected by US Patent 11,400,077

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Famygen Life Sci RYZUMVI phentolamine mesylate SOLUTION;OPHTHALMIC 217064-001 Sep 25, 2023 RX Yes Yes ⤷  Start Trial ⤷  Start Trial TREATMENT OF PHARMACOLOGICALLY-INDUCED MYDRIASIS ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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