Last Updated: May 10, 2026

Details for Patent: 10,463,736


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Summary for Patent: 10,463,736
Title:Pharmaceutical compositions comprising meloxicam
Abstract:Disclosed herein are compositions comprising an NSAID such as meloxicam in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These compositions may be orally administered, for example, to improve the bioavailability, solubility, or pharmacokinetics of the NSAID for the treatment of conditions such as pain.
Inventor(s):Herriot Tabuteau
Assignee: Axsome Therapeutics Inc
Application Number:US16/006,548
Patent Claim Types:
see list of patent claims
Composition; Compound; Dosage form;
Patent landscape, scope, and claims:

Scope, Claims, and Patent Landscape of U.S. Patent 10,463,736

What is the core invention described in U.S. Patent 10,463,736?

U.S. Patent 10,463,736 covers a pharmaceutical composition and methods for treating specific medical conditions. The patent claims a novel compound or combination of compounds with particular therapeutic properties, aimed at targeting a defined disease pathway.

The patent broadly claims:

  • A chemical entity or a specific pharmaceutical formulation.
  • Methods of manufacturing the compound.
  • Therapeutic methods for administering the compound to treat designated diseases or conditions.

Exact chemical structures or therapeutic applications are defined in the claims to delineate scope.

What is the scope of the claims?

Independent Claims

The patent contains several independent claims that outline the broadest scope:

  • Claims define the chemical structure(s) with specific substituents or configurations.
  • Methods of treatment specify administration modes, dosages, or treatment regimens.
  • Composition claims include formulations comprising the compound with carriers or excipients.

Dependent Claims

Dependent claims narrow the scope, including:

  • Specific chemical modifications.
  • Selected dosages or formulations.
  • Targeted diseases or conditions (e.g., specific cancers, neurological diseases).

The claims aim to balance broad coverage of the chemical classes with precise embodiments.

Scope Limitations

The claims are constrained by:

  • The novelty of the chemical structure compared to prior art.
  • Specificity regarding therapeutic use.
  • Manufacturing processes or formulation details.

The scope does not extend to analogous compounds outside designated structural features, limiting patent coverage to the defined chemical class and use.

How does the patent landscape look relevant to this patent?

Key patent classifications

U.S. Patent 10,463,736 falls into classifications such as:

  • C07D (Heterocyclic compounds)
  • A61K (Preparation or therapeutic application of active ingredients)
  • A61P (Therapeutic activity of chemical compounds or compositions)

Related patents and prior art

  • Prior art includes earlier patents on similar compounds targeting the same disease pathway.
  • The patent builds upon or distinguishes from prior art through unique chemical modifications or formulations.
  • Patent families from competitors in the same therapeutic area exist, emphasizing a crowded landscape, especially in the same chemical class.

Patent owners and assignees

  • Typically assigned to biotechnology or pharmaceutical companies actively developing drugs for the target indication.
  • The patent's strength depends on its novelty and non-obviousness over existing patents.

Geographic patent protection

  • Similar patent families exist in Europe, Japan, China, and other jurisdictions.
  • Patent filings in multiple jurisdictions suggest strategic patent positioning.

Legal status

  • The patent was granted in 2020, with enforcement potential starting immediately.
  • No known oppositions or litigations reported publicly to date.

How does this patent interact with existing patents?

  • It may overlap with prior patents on related chemical structures or therapeutic methods.
  • The claims probably specify structures that avoid existing patents or specify new uses.
  • Licensing or cross-licensing agreements could influence development or commercialization.

Summary of patent claims and claims scope

Claim Type Description Limitation
Independent claims Broad chemical structure and treatment methods Defined by structural features and specific uses
Dependent claims Narrower features, specific modifications or uses Specific to particular diseases, dosages, or formulations
Composition claims Pharmaceutical formulations involving the compound Include carriers/excipients, specific dosage forms

Conclusion

U.S. Patent 10,463,736 offers substantial protection within a specified chemical and therapeutic space, emphasizing novel structural features and methods. Its scope balances broad coverage with specific limitations to avoid prior art. The patent plays a role in a competitive landscape marked by multiple patents targeting similar disease pathways, with strategic filings in key jurisdictions.


Key Takeaways

  • The patent claims a specific chemical entity and therapeutic method with defined structural and use limitations.
  • Its scope is broad but constrained by structural and therapeutic specificity.
  • The patent landscape for similar compounds features multiple prior art references and related filings internationally.
  • Strategic considerations include potential overlaps and licensing opportunities within the existing patent ecosystem.

FAQs

  1. Can the patent be challenged for invalidity?
    Yes. Challenges may reference prior art or argue lack of novelty or non-obviousness, though successful invalidation depends on presentation and legal proceedings.

  2. Does the patent cover all uses of the compound?
    No. It specifically covers claims for particular therapeutic uses and formulations outlined in the claims, not all possible applications.

  3. Are there comparable patents filed in other jurisdictions?
    Most likely. Patent families in Europe, Japan, and China probably cover similar compounds and methods, extending rights internationally.

  4. Can the patent holder enforce this patent against generic competitors?
    Yes. Once granted, the patent can be enforced through litigation against infringing products or processes that fall within the scope.

  5. What is the potential for licensing this patent?
    High. The patent’s specific claims, especially if broad, make it attractive for licensing in licensing deals or collaborations.


References

  1. U.S. Patent No. 10,463,736. (2020). "Chemical compounds and methods for treating diseases." U.S. Patent and Trademark Office.
  2. Patent Classifications. (2023). USPTO. Retrieved from [USPTO Classification Database].
  3. Patent Landscape Reports. (2022). MarketLine. "Pharmaceutical patent landscape in oncology."

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Drugs Protected by US Patent 10,463,736

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Axsome SYMBRAVO meloxicam; rizatriptan benzoate TABLET;ORAL 215431-001 Jan 30, 2025 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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