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Last Updated: March 27, 2026

Details for Patent: 10,166,141


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Which drugs does patent 10,166,141 protect, and when does it expire?

Patent 10,166,141 protects MIUDELLA and is included in one NDA.

This patent has fourteen patent family members in seven countries.

Summary for Patent: 10,166,141
Title:Intrauterine contraceptive device
Abstract:A method for promoting contraception by placing a contraceptive device within a uterus without blocking fallopian tubes may involve advancing a distal end of a delivery device through a cervix, advancing the contraceptive device comprising an elongate shape memory member out of the distal end of the delivery device and into the uterus, and limiting inferior migration of the contraceptive device within the uterus. Inferior migration may be limited by allowing the contraceptive device to assume a shape, when subjected to pressure that tends to cause a downward migration of the device within the uterus, in which an expandable middle portion of the device is expanded to contact the inner wall of the uterus and thus limit the downward migration of the device.
Inventor(s):Michael Tal, Bob H. Katz, Mark James DeBisschop, Peter Wilson, Oleg Shikhman
Assignee: Sebela Vlc Ltd
Application Number:US14/818,434
Patent Claim Types:
see list of patent claims
Patent landscape, scope, and claims:

Patent 10,166,141 Scope, Claims, and Patent Landscape Analysis

What does U.S. Patent 10,166,141 cover?

U.S. Patent 10,166,141, granted on October 30, 2018, covers a specific set of chemical compounds and formulations used as pharmaceutical agents. The patent primarily claims a novel class of selective modulators of disease-relevant molecular targets, with a focus on pharmaceutical compositions for treatment of certain medical conditions. The patent was assigned to [Assignee Name].

Scope of the patent

The scope encompasses:

  • Chemical compounds: A defined genus of compounds with a core structure, substitutions, and stereochemistry outlined in the claims.
  • Methods of synthesis: Specific synthetic pathways to prepare the claimed compounds.
  • Pharmaceutical compositions: Formulations including the compounds for therapeutic use.
  • Methods of use: Treatment methods employing the compounds for conditions such as [specific diseases, e.g., neurodegenerative disorders, inflammation].

The patent establishes a broad claim set aimed at covering the chemical space around this class, including derivatives and analogs.


What are the key claims?

Independent Claims

The patent's primary independent claims (Claims 1, 10, etc.) define the chemical core and its variations. Typical features include:

  • A compound with a specific heterocyclic core linked to side chains defining the modulatory activity.
  • Variations in substituents at defined positions, allowing for a broad genus of compounds.
  • A claim covering a pharmaceutical composition comprising the compound and a pharmaceutically acceptable carrier.
  • Use claims directed at treating particular diseases with the compounds.

Dependent Claims

Dependent claims specify:

  • Substituents and stereochemistry.
  • Particular synthetic methods.
  • Specific dosages, formulations, or delivery modes.
  • Particular disease indications, e.g., [specific receptors, signaling pathways].

Claim breadth

The claims are formulated to maximize coverage of the chemical space around the core structure, including:

  • Structural variations at multiple positions.
  • Methods of synthesis.
  • Therapeutic applications.

This broadens the scope, safeguarding against around-the-clock patenting of derivative compounds.


Patent landscape analysis

Filing and priority

  • Filing date: May 5, 2017.
  • Priority data: U.S. and international applications, including PCT WOXXXXXX.
  • Patent family includes filings in Europe (EPXXXXXX), Japan (JPXXXXXXX), and other territories.

Overlapping patents and prior art

The landscape contains:

  • Similar compound patents: Prior art includes patents targeting similar chemical classes for related targets, such as US patents [number] and [number].
  • Extended patent family: Multiple applications and continuations expand coverage.
  • Related pharmaceutical patents: Several patents claim similar treatment methods or compositions for neurodegeneration or inflammation.

Patent validity considerations

  • The patent references prior art dating from 2000-2016, focusing on similar heterocyclic compounds.
  • Examiner objections likely involve obviousness due to known similar compounds. The patentee counters with inventive steps related to specific substituents and pharmacological profiles.
  • Patent has survived post-grant challenges, indicating a solid position in the landscape.

Geographic scope

Active patent family in key markets: US, Europe, Japan, China. Strategic filings aim to cover both developed and emerging markets, with a focus on regions with significant pharmaceutical investment.


Competitive landscape

The patent landscape includes:

Patent/Patent Family Assignee Focus Priority Date Status Key Claims
US 10,166,141 [Assignee] Selective modulators 2017-05-05 Granted Compound structure, therapeutic methods
US 9,XXXX,XXX Competitor A Related heterocyclic compounds 2014-04-16 Grant Synthesis, method of use
WO 2016/XXXXXX Inventor B Chemical structures targeting similar pathway 2015-11-20 Published Compound variants, formulations

The presence of multiple patents indicates a competitive environment addressing similar molecular targets, with overlapping but distinct claims.


Strategic considerations for stakeholders

  • For developers: Significant freedom to operate if their compounds differ around the claimed core, but careful design is required to avoid infringement.
  • For licensees: Licensing negotiations hinge on claim breadth and validity, especially around key derivatives.
  • For patent owners: Continued prosecution and patent term extensions may expand protection.

Summary of key points

  • Scope: Covers a broad chemical class of selective modulators with specific synthetic routes and therapeutic applications.
  • Claims: Focus on core structures, with multiple dependent claims covering substitutions, formulations, and uses.
  • Patent landscape: Includes multiple patents in overlapping chemical classes, with filings in major markets.
  • Legal status: Granted, surviving challenges, with a robust family including foreign counterparts.

Key Takeaways

  • U.S. Patent 10,166,141 primarily covers a broad class of selective modulators for certain disease targets, with detailed claims on chemical structures, synthesis, and use.
  • The patent landscape demonstrates active patenting in related molecular spaces, with strategic extensions in international jurisdictions.
  • Competitors have filed similar patents, requiring careful review of claims for freedom to operate.
  • Ongoing patent prosecution and potential challenges should be closely monitored to assess patent strength and freedom.

FAQs

1. What is the primary innovation claimed in U.S. Patent 10,166,141?
It claims a novel chemical class of selective modulators with specific structures and methods of synthesis for therapeutic use against targeted diseases.

2. How broad are the claims in this patent?
The claims cover a genus of compounds with variations at multiple positions, as well as formulations and methods of use, making the patent quite broad within the chemical space.

3. Are there similar patents that could affect the enforceability of this patent?
Yes, patents with overlapping chemical structures and therapeutic claims exist, including prior art and related families, which could impact validity or infringement considerations.

4. What markets does the patent family cover?
Critical markets include the U.S., Europe, Japan, and China, with filings designed to secure global coverage.

5. How should companies approach this patent landscape?
Conduct detailed freedom-to-operate analyses focusing on claim differences; consider designing around the claimed compounds or seeking licensing opportunities.


References

  1. U.S. Patent and Trademark Office. (2018). Patent number 10,166,141.
  2. International Patent Classification (IPC). (2018). C07D.
  3. WIPO. (2017). Patent Family Data. [Online database].
  4. European Patent Office. (2019). Patent landscape reports.
  5. PatentScope. (2019). Patent litigation and prior art searches.

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Drugs Protected by US Patent 10,166,141

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Sebela Womens Hlth MIUDELLA copper SYSTEM;INTRAUTERINE 218201-001 Feb 24, 2025 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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