➤ Get the DrugPatentWatch Daily Briefing

Get Daily Updates on Generic Entry, Litigation, Biosimilars, and more …

Serving leading biopharmaceutical companies globally:

McKinsey
Baxter
Boehringer Ingelheim
AstraZeneca
Johnson and Johnson
Dow

Last Updated: September 21, 2021

DrugPatentWatch Database Preview

Claims for Patent: 9,399,014


Email this page to a colleague

« Back to Dashboard

Summary for Patent: 9,399,014
Title:Pharmaceutical topical compositions
Abstract: The invention provides pharmaceutical stable semisolid topical compositions comprising between 0.2 to 5% of a des-fluoroquinolone compound, and a suitable carrier to manufacture an ointment or a cream.
Inventor(s): Tarrago; Cristina (Esplugues del Llobregat, ES), Santos; Benjamin (Barcelona, ES), Raga; Manuel (Barcelona, ES), Guglietta; Antonio (Molins de Rei, ES)
Assignee: FERRER INTERNACIONAL, S.A. (Barcelona, ES)
Application Number:14/197,933
Patent Claims: 1. A method of treatment of skin and skin structure bacterial infections caused by S. aureus or S. pyrogenes comprising: administering a stable topical cream composition to a subject in need thereof, said stable composition comprising: a) 0.2-5% of ozenoxacin, and b) a suitable carrier comprising: b.1) 15-25% of one or more emulsifiers selected from the group consisting of ethylene glycol monostearate, sorbitan tristearate, a mixture of PEG6 stearate, glycol stearate and PEG32 stearate, and hydrogenated lecithin, and mixtures thereof; b.2) 10-20% of one or more surfactants selected from the group consisting of sorbitan oleate monoolein/propylene glycol, C.sub.8C.sub.10 fatty acid mono- and diglycerides from coconut oil, soy lecithin, egg phosphatides, citric acid esters of monoglycerides, lactic acid esters of monoglycerides, diacetyl tartaric acid esters of monoglycerides, succinic acid esters of monoglycerides, sucrose fatty acid esters, polyglycolyzed glycerides of oleic acids, polyglycolyzed glycerides of linoleic acid, polyglycerol esters of fatty acids, and polyglyceryl esters of mixed fatty acids, and mixtures thereof; b.3) 5-15% of an oil component which is the Guerbet alcohol 2-octyl dodecanol; b.4) 1-10% of one or more low melting point waxes selected from the group consisting of fatty alcohols having 8 to 30 carbon atoms and mixtures thereof; b.5) water; b.6) 10-20% of one or more water dispersible components selected from the group consisting of polyethylene glycol 400, hexylene glycol, propylene glycol, polypropylene glycol-10 methylglucose ether, ethoxydiglycol, polyethylene glycol-6 caprylic/capric glyceride, ethylene glycol monobutyl ether, polyethylene glycol-8 caprylic/capric glycerides, 3-methoxy-3-methyl-1-butanol, dimethyl isosorbide, and mixtures thereof; and b.7) 0.01-1% of one or more non-formaldehyde-donating preservatives; wherein the amount of component b.5 is an amount to complete 100 percent by weight and all percentages being weight percent and based on the total weight of the composition.

2. The method of treatment of skin and skin structure infections according to claim 1, wherein the skin and skin structure infection is impetigo.

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Medtronic
Boehringer Ingelheim
Baxter
Mallinckrodt
Johnson and Johnson
AstraZeneca

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.