.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Claims for Patent: 9,365,514

« Back to Dashboard

Claims for Patent: 9,365,514

Title:Composition comprising tetracyclic compound
Abstract: A composition which comprises substance represented by Formula (I), ##STR00001## [Meanings of the symbols that are included in the formula are given in the specification as definitions] a pharmaceutically acceptable carrier, and a dissolution aid is useful for improving solubility, oral absorbability and/or absorbability in blood of a poorly water-soluble or water insoluble tetracyclic compounds having an ALK inhibitory activity that are useful as a prophylactic and/or therapeutic agent for cancer, depression, and cognitive function disorder.
Inventor(s): Furumoto; Kentaro (Gotemba, JP), Shiraki; Koji (Gotemba, JP), Hirayama; Tomoaki (Tokyo, JP)
Assignee: Chugai Seiyaku Kabushiki Kaisha (Tokyo, JP)
Application Number:13/816,804
Patent Claims: 1. A composition comprising a substance which is 9-Ethyl-6,6-dimethyl-8-(4-morpholin-4-yl-piperidin-1-yl)-11-oxo-6,11-dihy- dro-5H-benzo[b]carbazole-3-carbonitrile or a salt thereof, a pharmaceutically acceptable carrier, and a dissolution aid, wherein the dissolution aid is sodium lauryl sulfate.

2. An orally administrable formulation comprising the composition described in claim 1.

3. The composition according to claim 1, wherein the composition further comprises an organic polymer which is selected the group consisting of hydroxypropyl cellulose, hydroxypropylmethyl cellulose, methyl cellulose, propylene glycol alginate ester, powdered agar, guar gum, zein, hydroxyethylmethyl cellulose, a carboxyvinyl polymer, polyvinyl alcohol, a vinyl acetate resin, sodium polystyrene sulfonate, casein, sodium caseinate, a carboxyvinyl polymer, copolyvidone, amino alkylmethacrylate copolymer E, polyvinylacetal diethylaminoacetate, methacrylic acid copolymer LD, methacrylic acid copolymer S, purified shellac, carboxymethylethyl cellulose, cellulose acetate phthalate, hydroxypropylmethyl cellulose acetate succinate, and a mixture thereof.

4. The composition according to claim 1, wherein said water solubility of the substance is less than 100 .mu.g/mL at 25.degree. C.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

How are People Using DrugPatentWatch?

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc