.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Claims for Patent: 9,216,178

« Back to Dashboard

Claims for Patent: 9,216,178

Title:Dry blend formulation of tetrahydrobiopterin
Abstract: Dry blend powder formulations comprising a pharmaceutical formulation containing tetrahydrobiopterin, and methods of making and using the same, are disclosed herein.
Inventor(s): Chou; Tianwei (El Cerrito, CA), Okhamafe; Augustus O. (Concord, CA)
Assignee: BioMarin Pharmaceutical Inc. (Novato, CA)
Application Number:13/666,697
Patent Claims: 1. A pharmaceutical composition, comprising a dry blend powder that comprises about 32% by weight of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride, about 54% by weight of mannitol, about 1.9% by weight of sucrolose, about 10.4% by weight of potassium citrate, and about 1.6% by weight of ascorbic acid; wherein at least 90% of the initial amount of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride in the pharmaceutical composition remains after the pharmaceutical composition is stored at 40.degree. C. and 75% relative humidity for a period of three months.

2. The pharmaceutical composition of claim 1, wherein the initial amount of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride in the pharmaceutical composition is in a range from about 100 mg to about 500 mg.

3. The pharmaceutical composition of claim 1, wherein the initial amount of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride in the pharmaceutical composition is about 100 mg.

4. The pharmaceutical composition of claim 1, wherein the initial amount of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride in the pharmaceutical composition is about 500 mg.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc