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Claims for Patent: 9,205,075

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Claims for Patent: 9,205,075

Title:Apparatus and method for reconstituting a pharmaceutical and preparing the reconstituted pharmaceutical for transient application
Abstract: An apparatus and method for preparing a pharmaceutical for transient application includes a tray having a sealed compartment, a vial of an ophthalmic formulation of mitomycin-C, a diluent carrier containing sterilized water, and a syringe that are all contained together in a single package. The component parts of the apparatus are used together to reconstitute the contents of the vial with the water in the diluent carrier, and then draw the reconstituted drug into the sealed compartment of the tray by a suction force produced by the syringe. In the tray compartment, the reconstituted drug is absorbed in at least one absorbent pad. The absorbent pads may come in multiple shapes and or/sizes. The tray is opened to remove the pad and the absorbed drug from the tray compartment for use of the pad in transient application of the drug.
Inventor(s): Timm; Edward J. (Cumming, GA)
Assignee: MOBIUS THERAPEUTICS, LLC (St. Louis, MO)
Application Number:13/445,654
Patent Claims: 1. A kit for applying an ophthalmic formulation of mitomycin-C to body tissue comprising: a) a sealed container of an ophthalmic formulation of mitomycin-C; b) a tray having a compartment with at least one sterile, absorbent pad, wherein: i) the at least one sterile, absorbent pad is removable from the tray compartment for transient application of the ophthalmic formulation to the body tissue; and ii) wherein the at least one sterile, absorbent pad comprises an array of pre-cut absorbent pads or sponges with sizes of from 3 to 6 mm, wherein said array comprises at least one rectangle and at least one half-moon and at least one wedge; c) a carrier operable to withdraw said ophthalmic formulation from said sealed container, and to deliver said ophthalmic formulation to said compartment in said tray; wherein: i) the tray has a first passage that extends between the tray compartment and an exterior of the tray that is communicable with the carrier for receiving the ophthalmic formulation; and ii) the tray is removably connectable with said carrier through said first passage.

2. The kit of claim 1, wherein said carrier comprises a sterile liquid, and is further operable to mix said sterile liquid with said ophthalmic formulation of mitomycin-C in said sealed container.

3. The kit of claim 1 wherein the tray has a cover that is movable between opened and closed positions for providing access to the compartment and the pad in the compartment.

4. The kit of claim 1, wherein said tray further comprises a second passage through which air is aspirated from said compartment.

5. The kit of claim 1, wherein said tray further comprises a second passage through which air is aspirated from said compartment, further comprising a syringe that is connectable to the tray through the second passage being operable to produce a suction force that is communicated to the tray compartment.

6. A kit for applying an sterile liquid pharmaceutical formulation to body tissue comprising: a) a sealed container of a sterile pharmaceutical formulation; b) a tray having a compartment with at least one sterile, absorbent pad, wherein: i) the at least one sterile, absorbent pad is removable from the tray compartment for transient application of the ophthalmic formulation to the body tissue; and ii) wherein the at least one sterile, absorbent pad comprises an array of pre-cut absorbent pads or sponges with sizes of from 3 to 6 mm, wherein said array comprises at least one rectangle and at least one half-moon and at least one wedge; c) a carrier operable to withdraw said formulation from said sealed container, and to deliver said formulation to said compartment in said tray; wherein: i) the tray has a first passage that extends between the tray compartment and an exterior of the tray that is communicable with the carrier for receiving the formulation; and ii) the tray is removably connectable with said carrier through said first passage.

7. The kit of claim 6, wherein said carrier comprises a sterile liquid, and is further operable to mix said sterile liquid with said ophthalmic formulation of mitomycin-C in said sealed container.

8. The kit of claim 6 wherein the tray has a cover that is movable between opened and closed positions for providing access to the compartment and the pad in the compartment.

9. The kit of claim 6, wherein said tray further comprises a second passage through which air is aspirated from said compartment.

10. The kit of claim 6, wherein said tray further comprises a second passage through which air is aspirated from said compartment, further comprising a syringe that is connectable to the tray through the second passage being operable to produce a suction force that is communicated to the tray compartment.
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