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Last Updated: April 5, 2026

Claims for Patent: 9,187,495

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Summary for Patent: 9,187,495

Title:	Compounds and methods for treating bacterial infections
Abstract:	Compounds of formula (I), pharmaceutically acceptable salts thereof, and uses of the compounds of formula (I) for treating bacterial infections are disclosed.
Inventor(s):	Gregory Steven Basarab, Madhusudhan Reddy Gowravaram, Sheila Irene Hauck, Fei Zhou
Assignee:	AstraZeneca UK Ltd , Entasis Therapeutics Inc
Application Number:	US14/515,684
Patent Claims:	1. A compound represented by the following structural formula: or a pharmaceutically acceptable salt thereof. 2. A pharmaceutical composition comprising a compound of claim 1, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient or diluent. 3. A method for treating a bacterial infection in a subject in need thereof comprising administering to the subject an effective amount of a compound as claimed in claim 1, or a pharmaceutically acceptable salt thereof. 4. A method for inhibiting bacterial DNA gyrase in a subject in need thereof, comprising administering to the subject an effective amount of a compound as claimed in claim 1, or a pharmaceutically acceptable salt thereof.

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