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Serving leading biopharmaceutical companies globally:

Julphar
Healthtrust
UBS
Covington
Cipla
Fish and Richardson
McKinsey
Deloitte
Cantor Fitzgerald
Accenture

Generated: December 17, 2017

DrugPatentWatch Database Preview

Claims for Patent: 9,145,389

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Claims for Patent: 9,145,389

Title:Benzimidazole compound crystal
Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-- 1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
Inventor(s): Fujishima; Akira (Hyogo, JP), Aoki; Isao (Hyogo, JP)
Assignee: Takeda Pharmaceutical Company Limited (Osaka, JP)
Application Number:14/508,651
Patent Claims: 1. A solid amorphous compound of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-- 1H-benzimidazole or salt thereof, having an optical purity of at least 98.3%.

2. The solid amorphous compound of claim 1, which is (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-- 1H-benzimidazole having an optical purity of at least 98.3%.

3. A crystalline compound of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-- 1H-benzimidazole or salt thereof, having an optical purity of at least 99.8%, produced by dissolving the solid amorphous compound or salt thereof of claim 1 in a solvent to form a solution and precipitating crystals from the solution.

4. A pharmaceutical composition comprising the crystalline compound of claim 3 and a pharmaceutically acceptable carrier.
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Serving leading biopharmaceutical companies globally:

Medtronic
Julphar
Federal Trade Commission
Cantor Fitzgerald
McKinsey
US Army
Covington
Colorcon
Deloitte
Farmers Insurance

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