|Title:||Methods for the administration of iloperidone|
|Abstract:|| The present invention relates to methods for treating a patient with iloperidone or a metabolite thereof, which patient is also being treated with fluoxetine, and lowering risk for QT prolongation.|
|Inventor(s):|| Wolfgang; Curt (Germantown, MD), Polymeropoulos; Mihael (Potomac, MD) |
|Assignee:|| Vanda Pharmaceuticals, Inc. (Washington, DC) |
1. A method of decreasing a risk of QT prolongation in a patient being treated for schizophrenia with iloperidone, the method comprising: administering to the patient a dose
of iloperidone that is 24 mg/day if, and because, the patient is not being treated with fluoxetine; and administering to the patient a dose of iloperidone that is 12 mg/day if, and because, the patient is being treated with fluoxetine.