Flexible Flat-Rate Plans

Flat-rate pricing for predictable budgeting

Short-term plans for project- or client-based billing

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Claims for Patent: 9,101,637

« Back to Dashboard

Claims for Patent: 9,101,637

Title:Methods of treating inflammation with compositions comprising lecithin oils and NSAIDS for protecting the gastrointestinal tract and providing enhanced therapeutic activity
Abstract: A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulsion for internal, oral, direct or topical administration.
Inventor(s): Lichtenberger; Lenard M. (Houston, TX)
Application Number:12/883,902
Patent Claims: 1. A method of reducing a GI toxic effect of a non-steroidal anti-inflammatory drug (NSAID) in a subject who ingests the NSAID, comprising administering the NSAID to the subject as an NSAID-in-oil suspension that comprises lecithin oil and an NSAID, wherein the lecithin oil consists of soy lecithin components in sunflower oil and has about 33 to about 40 wt. % of phosphatidylcholine (PC), about 26 to about 31 wt. % triglycerides, about 8 to about 13 wt. % free fatty acids, and about 5 to about 9 wt. % glycolipids, and wherein the NSAID is in an association complex with a phospholipid of the lecithin oil.

2. The method of claim 1, wherein said GI toxic effect is at least one effect selected from the group consisting of GI bleeding and GI tract ulceration.

3. The method of claim 1, wherein said NSAID is selected from the group consisting of aspirin, indomethacin, and ibuprofen.

4. The method of claim 3, wherein said NSAID is aspirin.

5. The method of claim 3, wherein said NSAID is ibuprofen.

6. The method of claim 1, wherein said subject suffers from at least one condition selected from the group consisting of tissue inflammation, tissue ulceration, pain, fever, cardiovascular disease, ovarian cancer, colon cancer, and Alzheimer's Disease.

7. The method of claim 6, wherein said subject suffers from cardiovascular disease.

8. The method of claim 3, wherein said NSAID is indomethacin.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

How are People Using DrugPatentWatch?

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.