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Claims for Patent: 9,056,100

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Claims for Patent: 9,056,100

Title:Quinuclidine derivatives and medicinal compositions containing the same
Abstract: Provided is a powder inhalant comprising 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicy- clo[2.2.2]octane bromide and methods of using the same.
Inventor(s): Fernandez Forner; Maria Dolors (Barcelona, ES), Prat Quinones; Maria (Barcelona, ES), Buil Albero; Maria Antonia (Barcelona, ES)
Assignee: ALMIRALL, S.A. (Barcelona, ES)
Application Number:14/311,102
Patent Claims: 1. A powder inhalant comprising 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicy- clo[2.2.2]octane bromide.

2. The powder inhalant of claim 1 further comprising a pharmaceutically acceptable carrier or diluent.

3. The powder inhalant of claim 2 wherein the pharmaceutically acceptable carrier or diluent is lactose.

4. The powder inhalant of claim 1 further comprising a .beta..sub.2 agonist.

5. The powder inhalant of claim 4 further comprising a steroid or a phosphodiesterase IV inhibitor.

6. The powder inhalant of claim 1 further comprising a steroid.

7. The powder inhalant of claim 6 further comprising a phosphodiesterase IV inhibitor.

8. The powder inhalant of claim 1 further comprising a phosphodiesterase IV inhibitor.

9. A method for treating chronic obstructive pulmonary disease, chronic bronchitis, bronchial hyperreactivity, asthma, or rhinitis which method comprises administering to a human or animal patient in need of such treatment an effective amount of the powder inhalant of claim 1.

10. The method of claim 9 further comprising administering an effective amount of a .beta..sub.2 agonist.

11. The method of claim 10 further comprising administering an effective amount of a steroid or a phosphodiesterase IV inhibitor.

12. The method of claim 9 further comprising administering an effective amount of a steroid.

13. The method of claim 12 further comprising administering an effective amount of a phosphodiesterase IV inhibitor.

14. The method of claim 9 further comprising administering an effective amount of a phosphodiesterase IV inhibitor.
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