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Last Updated: March 28, 2024

Claims for Patent: 8,969,412


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Summary for Patent: 8,969,412
Title:Use for a composition comprising chloroprocaine HCL, a new composition comprising chloroprocaine HCL and a method for its manufacture
Abstract: The present invention concerns a new use for a composition containing chloroprocaine HCl, and in particular its use for the manufacture of a drug for intrathecal narcosis. The present invention also concerns a new composition containing chloroprocaine HCl, being particularly suited to this new use, as well as a new method for manufacturing the composition.
Inventor(s): Mitidieri; Augusto (Morcote, CH), Donati; Elisabetta (Cavallasca, IT)
Assignee: Sintetica S.A. (Mendrisio, CH)
Application Number:11/991,449
Patent Claims: 1. A method for inducing a regional anaesthesia to a subject in need thereof which comprises the intrathechal administration of a composition consisting essentially of, per ml of solution in water for injection, the following substances: 9-11 mg chloroprocaine HCl; 6-8 mg NaCl; HCl in a sufficient quantity to impart a pH of 3.0-4.0; and water for injection, wherein the composition is a preservative-free composition.

2. The method as claimed in claim 1, wherein the composition has an osmolality of between 270 and 300 mOsm/kg.

3. The method as claimed in claim 1, wherein the composition has a relative density at 20.degree. C. of between 1.0070 and 1.0080.

4. A pharmaceutical composition for inducing a regional anaesthesia by intrathechal administration in the form of an aqueous solution consisting essentially of, per ml of solution in water for injection, the following substances: 9-11 mg chloroprocaine HCl, 6-8 mg NaCl, HCl in a sufficient quantity to impart a pH of 3.0-4.0, and water for injection, wherein the composition is a preservative-free composition.

5. The composition as claimed in claim 4, wherein the composition has an osmolality of between 270 and 300 mOsm/kg.

6. The composition as claimed in claim 4, wherein the composition has a relative density at 20.degree. C. of between 1.0070 and 1.0080.

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