Deep knowledge on
small-molecule drugs and
the 110,000 global patents
Proactively manage your pharmacy inventory
Drug patents …
… from Kazakhstan to Kalamazoo
Find generic entry opportunities
Manage your formulary budget
Anticipate generic drug launch
Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Title:||Dose mechanism for an injection device for limiting a dose setting corresponding to the amount of medicament left|
|Abstract:||A mechanism for preventing setting of a dose, which exceeds the amount of a medicament in a reservoir in an injection device. The device comprises a threaded piston rod, a limiter and a driver. The three elements are arranged such that during dose setting, the limiter is moved towards an end-of-contend position, wherein dose setting is limited. The invention comprises an accumulative and a non-accumulative embodiment. The invention further relates to a mechanism for prevention ejection of a dose exceeding the set dose.|
|Inventor(s):||Enggaard; Christian Peter (Hillerod, DK), Moller; Claus Schmidt (Fredensborg, DK), Markussen; Tom Hede (Bagsvaerd, DK)|
|Assignee:||Novo Nordisk A/S (Bagsvaerd, DK)|
1. A mechanism for preventing setting of a dose which exceeds the amount of a medicament in a reservoir in an injection device, wherein a dose is set by rotating a
dose setting member of a dose setting mechanism, the mechanism comprising: a piston rod having a threaded outer surface, wherein the piston rod rotates and translates axially forward during expelling of medication from the reservoir; a limiter that
prevents the setting of a dose which exceeds the amount of medication in a reservoir in the device, the limiter defining a passage for the piston rod; a driver defining a passage for the limiter, the driver being coupled to the dose setting member such
that rotation of the dose setting member during dose setting causes the driver to rotate; and wherein the limiter is coupled to the driver and the piston rod such that relative rotation between the driver and the piston rod during dose setting causes
the limiter to move towards a stopping position.
2. A mechanism according to claim 1, further comprising a housing defining a passage for the piston rod, the passage having a threaded inner surface for engagement with the threaded outer surface of the piston rod, the housing being arranged with respect to the piston rod such that rotation of the piston rod in relation to the housing causes the piston rod to be displaced relative to the housing in a longitudinal direction.
3. A mechanism according to claim 1, further comprising a locking means for locking the piston rod against rotation in at least one direction relative to the housing.
4. A mechanism according to claim 1, wherein: the limiter has a threaded outer surface and is rotationally retained in relation to the piston rod; and the passage of the driver has a threaded inner surface for engagement with the threaded outer surface of the limiter.
5. A mechanism according to claim 1, wherein the limiter comprises a first engaging surface adapted to engage a corresponding second engaging surface of the driver.
6. A mechanism according to claim 1, wherein the limiter comprises a plurality of teeth adapted to engage corresponding teeth of the housing and/or the driver when the limiter is in the stopping position.
7. A mechanism according to claim 1, wherein: the passage of the limiter has a threaded inner surface for engagement with the threaded outer surface of the piston rod; and the driver is rotationally retained in relation to the limiter.
8. A mechanism according to claim 1, wherein the limiter comprises a first engaging surface adapted to engage a corresponding second engaging surface of the piston rod.
9. A mechanism according to claim 5, wherein the threaded outer surface of the piston rod comprises the first engaging surface and the threaded inner surface of the driver comprises the second engaging surface.
10. A mechanism according to claim 1, further comprising a ratchet mechanism interconnecting the driver and the housing.
11. A mechanism according to claim 10, wherein the ratchet mechanism comprises a first and a second part, the first part being coupled to the driver and the second part being adapted to be locked for rotation relative to the housing by means of the locking means.
12. A mechanism according to claim 10, further comprising an ejection assisting system for providing an ejection force for assisting an operator during ejection.
13. A syringe device according to claim 12, wherein the ejection assisting system comprises a spring which is strained when the dose setting member is rotated during dose setting.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.