Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Abstract:||Levalbuterol L-tartrate affords crystals possessing properties desirable for use in a metered dose inhaler.|
|Inventor(s):||McGlynn; Paul (Marlborough, MA), Bakale; Roger (Shrewsbury, MA), Sturge; Craig (Falmouth, CA)|
1. An aerosol formulation comprising (a) crystalline levalbuterol L-tartrate, (b) ethanol, and (c) a propellant, wherein particles comprising crystalline levalbuterol
L-tartrate from the formulation have a mass median aerodynamic diameter from 1 to 10 microns as measured by an Andersen Cascade Impactor, wherein the crystalline levalbuterol L-tartrate is in the form of needle-like particles, wherein the crystalline
levalbuterol L-tartrate is in the form of needle-like particles.
2. The aerosol formulation of claim 1, wherein the particles comprising crystalline levalbuterol L-tartrate have a mass median aerodynamic diameter of from 1 to 5 microns.
3. The aerosol formulation of claim 1, wherein ethanol is present in an amount up to 10% by weight of the aerosol formulation.
4. The aerosol formulation of claim 3, wherein ethanol is present in an amount from 2% to 6% by weight of the aerosol formulation.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.