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Last Updated: December 28, 2025

Claims for Patent: 8,765,153

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Summary for Patent: 8,765,153

Title:	Levalbuterol salt
Abstract:	Levalbuterol L-tartrate affords crystals possessing properties desirable for use in a metered dose inhaler.
Inventor(s):	Paul McGlynn, Roger Bakale, Craig Sturge
Assignee:	Lupin Inc
Application Number:	US13/873,084
Patent Claims:	1. An aerosol formulation comprising (a) crystalline levalbuterol L-tartrate, (b) ethanol, and (c) a propellant, wherein particles comprising crystalline levalbuterol L-tartrate from the formulation have a mass median aerodynamic diameter from 1 to 10 microns as measured by an Andersen Cascade Impactor, wherein the crystalline levalbuterol L-tartrate is in the form of needle-like particles, wherein the crystalline levalbuterol L-tartrate is in the form of needle-like particles. 2. The aerosol formulation of claim 1, wherein the particles comprising crystalline levalbuterol L-tartrate have a mass median aerodynamic diameter of from 1 to 5 microns. 3. The aerosol formulation of claim 1, wherein ethanol is present in an amount up to 10% by weight of the aerosol formulation. 4. The aerosol formulation of claim 3, wherein ethanol is present in an amount from 2% to 6% by weight of the aerosol formulation.

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