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Generated: August 22, 2017

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Title:Nucleoside phosphoramidate prodrugs
Abstract: Disclosed herein are phosphoramidate prodrugs of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomer, salt (acid or basic addition salt), hydrate, solvate, or crystalline form thereof, represented by the following structure: ##STR00001## Also disclosed are methods of treatment, uses, and processes for preparing each of which utilize the compound represented by formula I.
Inventor(s): Du; Jinfa (Redwood City, CA), Nagarathnam; Dhanapalan (Bethany, CT), Sofia; Michael Joseph (Doylestown, PA), Wang; Peiyuan (Totowa, NJ)
Assignee: Gilead Pharmasset LLC (Foster City, CA)
Application Number:14/057,675
Patent Claims: >Claims of U.S. Appl. No. 14/013,237 as amended Aug. 30, 2013. cited by applicant .
U.S. Appl. No. 13/956,195, filed Jul. 31, 2013. cited by applicant .
Claims of U.S. Appl. No. 13/956,195 as amended Oct. 21, 2013. cited by applicant.

Primary Examiner: Lewis; Patrick
Attorney, Agent or Firm: Fitzpatrick, Cella, Harper & Scinto
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