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Claims for Patent: 8,573,210

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Claims for Patent: 8,573,210

Title:Nitric oxide delivery device
Abstract: A nitric oxide delivery device including a valve assembly, a control module and a gas delivery mechanism is described. An exemplary gas delivery device includes a valve assembly with a valve and circuit including a memory, a processor and a transceiver in communication with the memory. The memory may include gas data such as gas identification, gas expiration and gas concentration. The transceiver on the circuit of the valve assembly may send wireless optical line-of-sight signals to communicate the gas data to a control module. Exemplary gas delivery mechanisms include a ventilator and a breathing circuit. Methods of administering gases containing nitric oxide are also described.
Inventor(s): Bathe; Duncan P. (Fitchburg, WI), Klaus; John (Cottage Grove, WI), Christensen; David (Cambridge, WI)
Assignee: INO Therapeutics LLC (Hampton, NJ)
Application Number:13/677,483
Patent Claims: 1. A nitric oxide delivery device comprising: a control module to deliver a gas comprising NO to a patient in an amount effective to treat or prevent hypoxic respiratory failure; and a valve assembly to deliver the gas comprising NO from a gas container containing the gas comprising NO to the control module, the valve assembly comprising: a valve attachable to the gas container containing the gas comprising NO, the valve including an inlet and an outlet in fluid communication and a valve actuator to open or close the valve to allow the gas comprising NO through the valve to the control module; and a circuit supported within the valve assembly and disposed between the actuator and a cap, the circuit including: a valve memory to store gas data comprising one or more of gas identification, gas expiration date and gas concentration in the gas container and a valve processor and a valve transceiver in communication with the valve memory to send and receive wireless optical line-of-sight signals to communicate the gas data to the control module and to verify one or more of the correct gas, the correct gas concentration and that the gas is not expired.

2. The nitric oxide delivery device of claim 1, where in the valve assembly further comprises a data input disposed on the actuator and in communication with said valve memory, to permit a user to enter the gas data into the valve memory.

3. The nitric oxide delivery device of claim 2, wherein the gas data is provided in a bar code disposed on the gas container and is entered into the data input by a user-operated scanning device in communication with the data input.

4. The nitric oxide delivery device of claim 1, wherein the valve comprises a power source; and the valve transceiver periodically sends the wireless optical line-of-sight signals to the control module, wherein the signals are interrupted by a duration of time at which no signal is sent.

5. The nitric oxide delivery device of claim 4, wherein the duration of time at which no signal is sent comprises about 10 seconds.

6. The nitric oxide delivery device of claim 1, wherein the control module comprises: a CPU transceiver to receive line-of-sight signals from the valve transceiver; a central processing unit (CPU) in communication with the CPU transceiver and including a CPU memory; and a display to enter patient information into the CPU memory, wherein the valve transceiver communicates the gas data to the CPU transceiver for storage in the CPU memory, and wherein the CPU compares the patient information entered into the CPU memory via the display and the gas data from the valve transceiver.

7. The nitric oxide delivery device of claim 6, wherein the valve comprises a timer including a calendar timer and an event timer, wherein the valve memory stores the date and time of opening and closing of the valve and the duration of time that the valve is open and the valve transceiver communicates the date and time of opening and closing of the valve to the CPU transceiver for storage in the CPU memory.

8. The nitric oxide delivery device of claim 6, wherein the CPU comprises an alarm that is triggered when the patient information entered into the CPU memory and the gas data from the valve transceiver do not match.

9. The nitric oxide delivery device of claim 6, wherein the CPU memory comprises instructions that cause the CPU processor to: receive gas data from the valve via a wireless optical line-of-sight signal with the valve connected to the gas container containing gas comprising NO; compare the gas data with user-inputted patient information; coordinate delivery of therapy to the patient with a medical device via the wireless optical line-of-sight signal between the CPU transceiver and the valve transceiver; select a therapy for delivery to a patient based on the received patient information; and control delivery of the selected therapy to the patient.

10. The nitric oxide delivery device of claim 9, wherein the CPU memory further comprises instructions that cause the CPU processor to: receive a first valve status selected from a first open position and a first closed position from a first valve via a first wireless optical line-of-sight signal with the first valve connected to a first gas container; receive a second valve status selected from a second open position and a second closed position from a second valve via a second wireless optical line-of-sight signal with the second valve connected to a second gas container; compare the first valve status and the second valve status; and emit an alarm if the first valve status comprises the first open position and the second valve status comprises the second open position.

11. The nitric oxide delivery device of claim 10, wherein the memory further comprises instructions that causes the CPU processor to: terminate delivery of therapy if the first valve status comprises the first open position and the second valve status comprises the second open position.

12. A method for treating or preventing hypoxic respiratory failure in a patient, the method comprising: providing the nitric oxide delivery device of claim 6; establishing communication between the valve transceiver and the CPU transceiver and communicating the gas data from the valve transceiver to the CPU; comparing the gas data communicated from the valve transceiver with patient information stored within the CPU memory; and delivering the gas comprising NO to the patient in an amount effective to treat or prevent hypoxic respiratory failure.

13. The method of claim 12, further comprising ceasing delivery of the gas comprising NO to the patient based on the comparison of the gas data and the patient information.

14. The method of claim 12, further comprising emitting an alert based on the comparison of the gas data and the patient information.

15. The method of claim 12, further comprising entering the gas data into the valve memory.

16. The method of claim 12, further comprising entering the patient information into the CPU memory.
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